Biocatalytic asymmetric amination of carbonyl functional group A synthetic biology approach to organic chemistry
文献类型:期刊论文
作者 | Dunming Zhu ; Ling Hua |
刊名 | Biotechnology Journal
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出版日期 | 2010-10 |
卷号 | 4期号:10页码:1420-1431 |
关键词 | Amino acid dehydrogenase Amino transfer Chiral amine Reductive amination Transaminase |
英文摘要 | Transaminases catalyze amino transfer reactions from amino donors such as amino acids or amines to keto acids or ketones to give chiral amino acid or amines in optically pure form. alpha-Amino acid dehydrogenases catalyze the asymmetric reductive amination of alpha-keto acids using ammonia as amino donor to furnish L-amino acids. The distinct features and synthetic application of these two enzymes are reviewed in an effort to illustrate their promising and challenging aspects in serving as approaches to the direct asymmetric synthesis of optically pure amines from the corresponding keto compounds, a formidable problem in organic chemistry. |
公开日期 | 2011-08-01 |
源URL | [http://localhost/handle/0/60] ![]() |
专题 | 天津工业生物技术研究所_生物催化与绿色化工 朱敦明_期刊论文 |
推荐引用方式 GB/T 7714 | Dunming Zhu,Ling Hua. Biocatalytic asymmetric amination of carbonyl functional group A synthetic biology approach to organic chemistry[J]. Biotechnology Journal,2010,4(10):1420-1431. |
APA | Dunming Zhu,&Ling Hua.(2010).Biocatalytic asymmetric amination of carbonyl functional group A synthetic biology approach to organic chemistry.Biotechnology Journal,4(10),1420-1431. |
MLA | Dunming Zhu,et al."Biocatalytic asymmetric amination of carbonyl functional group A synthetic biology approach to organic chemistry".Biotechnology Journal 4.10(2010):1420-1431. |
入库方式: OAI收割
来源:天津工业生物技术研究所
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