Exploring drug combinations in genetic interaction network
文献类型：期刊论文
| 作者 | Wang, Yin-Ying1,2; Xu, Ke-Jia1,2; Song, Jiangning3,4; Zhao, Xing-Ming1 |
| 刊名 | BMC BIOINFORMATICS
 |
| 出版日期 | 2012-05-08 |
| 卷号 | 13期号:Suppl. 7页码:S7 |
| 关键词 | IDENTIFICATION TAMOXIFEN DISEASES TARGETS CANCER MODEL |
| 英文摘要 | Background: Drug combination that consists of distinctive agents is an attractive strategy to combat complex diseases and has been widely used clinically with improved therapeutic effects. However, the identification of efficacious drug combinations remains a non-trivial and challenging task due to the huge number of possible combinations among the candidate drugs. As an important factor, the molecular context in which drugs exert their functions can provide crucial insights into the mechanism underlying drug combinations. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Mathematical & Computational Biology |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Mathematical & Computational Biology |
| 关键词[WOS] | IDENTIFICATION ; TAMOXIFEN ; DISEASES ; TARGETS ; CANCER ; MODEL |
| 收录类别 | SCI ; ISTP |
| 语种 | 英语 |
| WOS记录号 | WOS:000303940000008 |
| 公开日期 | 2012-08-29 |
| 源URL | [http://localhost/handle/0/257]  |
| 专题 | 天津工业生物技术研究所_结构生物信息学和整合系统生物学实验室 宋江宁_期刊论文 |
| 作者单位 | 1.Shanghai Univ, Inst Syst Biol, Shanghai 200444, Peoples R China 2.Shanghai Univ, Dept Math, Shanghai 200444, Peoples R China 3.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China 4.Monash Univ, Dept Biochem & Mol Biol, Melbourne, Vic 3800, Australia |
| 推荐引用方式 GB/T 7714 | Wang, Yin-Ying,Xu, Ke-Jia,Song, Jiangning,et al. Exploring drug combinations in genetic interaction network[J]. BMC BIOINFORMATICS,2012,13(Suppl. 7):S7. |
| APA | Wang, Yin-Ying,Xu, Ke-Jia,Song, Jiangning,&Zhao, Xing-Ming.(2012).Exploring drug combinations in genetic interaction network.BMC BIOINFORMATICS,13(Suppl. 7),S7. |
| MLA | Wang, Yin-Ying,et al."Exploring drug combinations in genetic interaction network".BMC BIOINFORMATICS 13.Suppl. 7(2012):S7. |
入库方式： OAI收割
来源：天津工业生物技术研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。