New Minor Spirostane Glycosides from Ypsilandra thibetica
文献类型：期刊论文
| 作者 | Zhang, Xu-Dong1,2; Chen, Chang-Xiang1 ; Yang, Jun-Yun1; Ni, Wei1; Liu, Hai-Yang1
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| 刊名 | HELVETICA CHIMICA ACTA
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| 出版日期 | 2012-07-01 |
| 卷号 | 95期号:7页码:1087-1093 |
| 关键词 | Ypsilandra thibetica Ypsilandrosides M?-?O Spirostanes Glycosides |
| ISSN号 | 0018-019X |
| 通讯作者 | Liu, HY (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China. ; haiyangliu@mail.kib.ac.cn |
| 英文摘要 | A further phytochemical investigation on the whole plants of Ypsilandra thibetica yielded three new spirostane glycosides, named ypsilandrosides MO (13). Their structures were established as (3 beta,11a,25R)-3,11-dihydroxyspirost-5-en-12-one 3-{O-a-L-rhanmopyranosyl-(1?4)-O-L-rhanmopyranosyl-(1?4)-O-[a-L-rhanmopyranosyl-(1?2)]-beta-D-glucopyranoside} (1), (3 beta,7 beta,25R)-spirost-5-ene-3,7-diol 3-{O-a-L-rhanmopyranosyl-(1?4)-O-a-L-rhanmopyranosyl-(1?4)-O-[a-L-rhanmopyranosyl-(1?2)]-beta-D-glucopyranoside} (2), and (3 beta,7a,25R)-spirost-5-ene-3,7,17-triol 3-{O-a-L-rhanmopyranosyl-(1?4)-O-a-L-rhanmopyranosyl-(1?4)-O-[a-L-rhanmopyranosyl-(1?2)]-beta-D-glucopyranoside} (3) by means of a combination of MS, 1D- and 2D-NMR spectroscopic methods, and chemical degradation. Among them, compound 3 is the first pennogenin (=(3 beta,25R)-spirost-5-ene-3,17-diol) saponin whose aglycone contains an OH group at C(7). Compounds 13 were evaluated for the inhibition of the growth of five tumor cell lines, but all of them proved to be inactive. |
| 学科主题 | Chemistry, Multidisciplinary |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | STEROIDAL SAPONINS ; NMR-SPECTROSCOPY |
| 收录类别 | SCI ; IC |
| 资助信息 | National Natural Science Funding of China[31170333]; Natural Science Foundation of Yunnan Province[2009CC019]; West Light Foundation of the Chinese Academy of Sciences[2908025712W1]; State Key Laboratory of Phytochemistry and Plant Resources in West China[540806321211]; Germplasm Bank of Wild Species and CAS Innovation Program of the Kunming Institute of Botany |
| 语种 | 英语 |
| WOS记录号 | WOS:000306277000005 |
| 公开日期 | 2012-09-03 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/15091]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xu-Dong,Chen, Chang-Xiang,Yang, Jun-Yun,et al. New Minor Spirostane Glycosides from Ypsilandra thibetica[J]. HELVETICA CHIMICA ACTA,2012,95(7):1087-1093. |
| APA | Zhang, Xu-Dong,Chen, Chang-Xiang,Yang, Jun-Yun,Ni, Wei,&Liu, Hai-Yang.(2012).New Minor Spirostane Glycosides from Ypsilandra thibetica.HELVETICA CHIMICA ACTA,95(7),1087-1093. |
| MLA | Zhang, Xu-Dong,et al."New Minor Spirostane Glycosides from Ypsilandra thibetica".HELVETICA CHIMICA ACTA 95.7(2012):1087-1093. |
入库方式： OAI收割
来源：昆明植物研究所
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