Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens
文献类型：期刊论文
| 作者 | Liu, Hong-Xin2,3; Bi, Jun-Long1; Wang, Yue-Hu2 ; Gu, Wei2,3; Su, Yao4; Liu, Fang4; Yang, Shi-Xian4; Hu, Guang-Wan2; Luo, Ji-Feng2; Yin, Ge-Fen1
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| 刊名 | HELVETICA CHIMICA ACTA
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| 出版日期 | 2012-07-01 |
| 卷号 | 95期号:7页码:1231-1237 |
| ISSN号 | 0018-019X |
| 关键词 | Pothos scandens Methyl pothoscandensate Antiviral activity X-Ray crystallography |
| 通讯作者 | Yin, GF (reprint author), Yunnan Agr Univ, Coll Anim Sci & Technol, Kunming 650201, Peoples R China. ; yingefen383@sohu.com ; long@mail.kib.ac.cn |
| 英文摘要 | Methyl pothoscandensate (1), a new molecular skeleton of ent-18(4?3)-abeokaurane, along with eight known compounds was isolated from the whole plant of Pothos scandens. The structure of the new compound was established by spectroscopic techniques and confirmed by single-crystal X-ray diffraction. The inhibitory activity of selected compounds against porcine respiratory and reproductive syndrome virus (PRRSV) was measured by the cytopathic effect (CPE) method. Compound 1 showed weak effect on PRRSV with an IC50 value of 40.3 +/- 8.3 mu M (TI=15.7). |
| 学科主题 | Chemistry, Multidisciplinary |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | TETRAZOLIUM SALT ; AGENTS |
| 资助信息 | National Natural Science Foundation of China[20972166, 31070288, 30860205, 31161140345]; Ministry of Education[B08044, MUC985-9] |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000306277000024 |
| 公开日期 | 2012-09-03 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/15127]  |
| 专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Yunnan Agr Univ, Coll Anim Sci & Technol, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 4.Yunnan Agr Univ, Coll Hort & Landscape, Kunming 650201, Peoples R China 5.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Hong-Xin,Bi, Jun-Long,Wang, Yue-Hu,et al. Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens[J]. HELVETICA CHIMICA ACTA,2012,95(7):1231-1237. |
| APA | Liu, Hong-Xin.,Bi, Jun-Long.,Wang, Yue-Hu.,Gu, Wei.,Su, Yao.,...&Long, Chun-Lin.(2012).Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens.HELVETICA CHIMICA ACTA,95(7),1231-1237. |
| MLA | Liu, Hong-Xin,et al."Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens".HELVETICA CHIMICA ACTA 95.7(2012):1231-1237. |
入库方式： OAI收割
来源：昆明植物研究所
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