Recognition and catalytic hydrolysis of adenosine 5′-triphosphate by cadmium (Ⅱ) ion and L-Glutamic acid
文献类型：期刊论文
| 作者 | Lv GX(吕功煊) ; Lv GX(吕功煊)
|
| 刊名 | J. Coord. Chem.
 |
| 出版日期 | 2011 |
| 卷号 | 64页码:3441-3453 |
| 关键词 | ATP Cd2þ L-Glutamic acid Recognition Catalytic hydrolysis |
| ISSN号 | 0095-8972 |
| 通讯作者 | 吕功煊 |
| 中文摘要 | Interactions among Cd2þ, glutamic acid (Glu), and adenosine 50-triphosphate (ATP) have been studied by potentiometric pH titration, IR, Raman, fluorescence, and NMR methods. In the Cd2þ–ATP binary system, the main interaction sites are the -, -, and -phosphate groups, N-1, and/or N-7. Cd2þ binds to the N-1 site at relatively low pH and binds to the N-7 site of adenosine ring of ATP with increasing pH. In the Cd2þ–Glu–ATP ternary system, ATP mainly binds to Cd2þ by the triphosphate chain. Oxygens of Glu coordinate with Cd2þ to form a complex to catalyze ATP hydrolysis. Hydrolysis of ATP catalyzed by the CdGlu complex was studied at pH 7.0 and 80 C by 31P-NMR spectrometry. Kinetics studies showed that the rate constant of ATP hydrolysis was 0.0199 min 1 in the ternary system, which is 9.9-fold faster than that in the ATP solution (2.01 10 3min 1). Hydrolysis occurs through an addition– elimination reaction mechanism with Cd2þ regulating the recognition and catalytic hydrolysis of ATP; water participates in the hydrolysis reaction of ATP at different steps with different functions in the ternary system. |
| 学科主题 | 环境催化与氢能 |
| 收录类别 | SCI |
| 资助信息 | the 973 Program under the Grant no. 2009CB22003 |
| 语种 | 英语 |
| 公开日期 | 2012-09-20 |
| 源URL | [http://210.77.64.217/handle/362003/299]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 兰州化学物理研究所_ERC国家工程研究中心 |
| 通讯作者 | Lv GX(吕功煊); Lv GX(吕功煊) |
| 推荐引用方式 GB/T 7714 | Lv GX,Lv GX. Recognition and catalytic hydrolysis of adenosine 5′-triphosphate by cadmium (Ⅱ) ion and L-Glutamic acid[J]. J. Coord. Chem.,2011,64:3441-3453. |
| APA | 吕功煊,&吕功煊.(2011).Recognition and catalytic hydrolysis of adenosine 5′-triphosphate by cadmium (Ⅱ) ion and L-Glutamic acid.J. Coord. Chem.,64,3441-3453. |
| MLA | 吕功煊,et al."Recognition and catalytic hydrolysis of adenosine 5′-triphosphate by cadmium (Ⅱ) ion and L-Glutamic acid".J. Coord. Chem. 64(2011):3441-3453. |
入库方式： OAI收割
来源：兰州化学物理研究所
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