Synthesis of Chiral Bulky Monophosphite Ligands and Their Application in Cu-Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Cyclic Enones
文献类型：期刊论文
| 作者 | Wang LL(王来来) ; Wang LL(王来来)
|
| 刊名 | Chin. J. Catal.
 |
| 出版日期 | 2010 |
| 卷号 | 31页码:514-517 |
| 关键词 | asymmetric 1 bulky monophosphite 2-cyclohexenone diethylzinc enantioselectivity 4-conjugate addition |
| ISSN号 | 1872-2067 |
| 通讯作者 | 王来来 |
| 中文摘要 | A series of new bulky monophosphite ligands were synthesized from axially chiral BINOL and highly sterically hindered adamantanecarbonyl chloride. These ligands were applied to the Cu-catalyzed asymmetric 1,4-conjugate addition of diethylzinc to cyclic enones and were found to have moderate enantioselectivities (up to 61% ee). The stereochemically matched combination of (S)-BINOL in ligand (S)-(2-(adamantane-1-carboxylic acid)-1,1’-binapthalen-2’-yl)-((S)-1,1’-binaphthalen-2,2’-yl)phosphite induces a moderate enantioselectivity. The sense of enantioselectivity is mainly controlled by the configuration of the 2,2’-o,o-(1,1’-binaphthyl)-dioxo-phosphite moiety of the ligands. |
| 学科主题 | 有机功能材料 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (20343005;20473107;20673130;20773147) |
| 语种 | 英语 |
| WOS记录号 | WOS:000278399400003 |
| 公开日期 | 2012-09-21 |
| 源URL | [http://210.77.64.217/handle/362003/473]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 通讯作者 | Wang LL(王来来); Wang LL(王来来) |
| 推荐引用方式 GB/T 7714 | Wang LL,Wang LL. Synthesis of Chiral Bulky Monophosphite Ligands and Their Application in Cu-Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Cyclic Enones[J]. Chin. J. Catal.,2010,31:514-517. |
| APA | 王来来,&王来来.(2010).Synthesis of Chiral Bulky Monophosphite Ligands and Their Application in Cu-Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Cyclic Enones.Chin. J. Catal.,31,514-517. |
| MLA | 王来来,et al."Synthesis of Chiral Bulky Monophosphite Ligands and Their Application in Cu-Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Cyclic Enones".Chin. J. Catal. 31(2010):514-517. |
入库方式： OAI收割
来源：兰州化学物理研究所
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