Direct Asymmetric Michael Addition of Thioether-based Aryl Sulfanyl-propan-2-one to Nitroalkenes Catalyzed by a Chiral Amine-Thiourea Bifunctional Organocatalyst
文献类型：期刊论文
| 作者 | Jiang XX(蒋先兴) ; Zhang BZ(张邦治) ; Zhang YF(张义福) ; Lin L(林利) ; Yan WJ(阎文锦) ; Wang R(王锐) |
| 刊名 | Chirality
 |
| 出版日期 | 2010 |
| 卷号 | 22页码:625-634 |
| 关键词 | asymmetric Michael addition aryl sulfanyl-propan-2-one nitroalkenes thiourea bifunctional organocatalyst |
| ISSN号 | 1520-636X |
| 通讯作者 | 王锐 |
| 中文摘要 | Although the organocatalytic direct asymmetric Michael reactions of carbonyl compounds to nitroalkenes have been investigated intensely, the Michael reaction of the thioether-based donors remains a rather undeveloped field. This work concerns the asymmetric Michael addition of aryl sulfanyl-propan-2-one to nitroalkenes with benzoic acid as an additive, and chiral amine-thiourea as a bifunctional organocatalyst. The reactions provided the highly functionalized chiral adducts with excellent enantioselectivities (up to 96% ee) and good yields. Moreover, the further transformed products exhibited excellent diastereoselectivity. |
| 学科主题 | 物理化学 |
| 收录类别 | SCI |
| 资助信息 | Natural Science Foundation of China (Contract grant numbers: 20525206;20772052;20621091);Chang Jiang Program of the Ministry of Education of China |
| 语种 | 英语 |
| WOS记录号 | WOS:000278832500001 |
| 公开日期 | 2012-09-21 |
| 源URL | [http://210.77.64.217/handle/362003/486]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Jiang XX,Zhang BZ,Zhang YF,et al. Direct Asymmetric Michael Addition of Thioether-based Aryl Sulfanyl-propan-2-one to Nitroalkenes Catalyzed by a Chiral Amine-Thiourea Bifunctional Organocatalyst[J]. Chirality,2010,22:625-634. |
| APA | 蒋先兴,张邦治,张义福,林利,阎文锦,&王锐.(2010).Direct Asymmetric Michael Addition of Thioether-based Aryl Sulfanyl-propan-2-one to Nitroalkenes Catalyzed by a Chiral Amine-Thiourea Bifunctional Organocatalyst.Chirality,22,625-634. |
| MLA | 蒋先兴,et al."Direct Asymmetric Michael Addition of Thioether-based Aryl Sulfanyl-propan-2-one to Nitroalkenes Catalyzed by a Chiral Amine-Thiourea Bifunctional Organocatalyst".Chirality 22(2010):625-634. |
入库方式： OAI收割
来源：兰州化学物理研究所
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