Highly Enantioselective Addition of Terminal Alkynes to Aldehydes Catalyzed by a New Chiral beta-Sulfonamide Alcohol/Ti((OPr)-Pr-i)(4)/Et2Zn/R3N Catalyst System
文献类型：期刊论文
| 作者 | Qiu L(邱立) ; Wang Q(王全) ; Lin L(林利) ; Liu XD(刘晓东) ; Jiang XX(蒋先兴) ; Zhao QY(赵庆阳) ; Hu GW(胡国文) ; Wang R(王锐) |
| 刊名 | Chirality
 |
| 出版日期 | 2009 |
| 卷号 | 21页码:316-323 |
| 关键词 | enantioselective addition sulfonamide alcohol tertiary amine base terminal alkynes aldehydes |
| ISSN号 | 0899-0042 |
| 通讯作者 | 王锐 |
| 中文摘要 | A new catalytic system, generated from the readily available and inexpensive b-sulfonamide alcohol L*, Ti(OiPr)4, Et2Zn, and tertiary amine base (R3N), effectively catalyzes the enantioselective addition of various terminal alkynes including some quite challenging alkynes to aldehydes in good yields and excellent enantioselectivities. Up to 96% yield and >99% enantioselectivity were achieved with the use of N,Ndiisoproylethylamine (DIPEA) as an additive in this asymmetric addition. |
| 学科主题 | 物理化学 |
| 收录类别 | SCI |
| 资助信息 | Natural Science Foundation of China (Contract grant numbers: 20525206;20772052;20621091);Ministry of Education of China (Chang Jiang Program) |
| 语种 | 英语 |
| WOS记录号 | WOS:000262561200009 |
| 公开日期 | 2012-09-21 |
| 源URL | [http://210.77.64.217/handle/362003/572]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Qiu L,Wang Q,Lin L,et al. Highly Enantioselective Addition of Terminal Alkynes to Aldehydes Catalyzed by a New Chiral beta-Sulfonamide Alcohol/Ti((OPr)-Pr-i)(4)/Et2Zn/R3N Catalyst System[J]. Chirality,2009,21:316-323. |
| APA | 邱立.,王全.,林利.,刘晓东.,蒋先兴.,...&王锐.(2009).Highly Enantioselective Addition of Terminal Alkynes to Aldehydes Catalyzed by a New Chiral beta-Sulfonamide Alcohol/Ti((OPr)-Pr-i)(4)/Et2Zn/R3N Catalyst System.Chirality,21,316-323. |
| MLA | 邱立,et al."Highly Enantioselective Addition of Terminal Alkynes to Aldehydes Catalyzed by a New Chiral beta-Sulfonamide Alcohol/Ti((OPr)-Pr-i)(4)/Et2Zn/R3N Catalyst System".Chirality 21(2009):316-323. |
入库方式： OAI收割
来源：兰州化学物理研究所
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