Stretching and imaging studies of single DNA molecules
文献类型：期刊论文
| 作者 | Zhang, Y（张益） ; Chen, SF ; Ouyang, ZQ ; Hu, J（胡钧） ; Xiong, QH ; Li, B（李宾） ; Huang, YB（黄一波） ; Li, MQ（李民乾） ; Jin, CZ |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2000 |
| 卷号 | 45期号:15页码:1365 |
| ISSN号 | 1001-6538 |
| 英文摘要 | DNA molecules were stretched on silanized mica surface with the molecular combing technique, and detected with fluorescence microscopy and atomic force microscopy. Meantime, DNA molecules were stretched with a modified dynamic molecular combing technique and studied with atomic force microscopy. The results indicate that, compared with the dynamic molecular combing technique, the modified dynamic molecular combing technique has advantages of less-sample demand and less contamination to sample; as compared with the molecular combing technique, it has better aligning effect and reproducibility. Combination of this kind of DNA molecular manipulating technique with the single DNA molecule detecting technique by atomic force microscopy and fluorescence microscopy will play an important role in the basic research of molecular dynamics and the application of gene research. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000089247500006 |
| 公开日期 | 2012-09-25 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/10171]  |
| 专题 | 上海应用物理研究所_中科院上海原子核所2003年前 |
| 推荐引用方式 GB/T 7714 | Zhang, Y,Chen, SF,Ouyang, ZQ,et al. Stretching and imaging studies of single DNA molecules[J]. CHINESE SCIENCE BULLETIN,2000,45(15):1365. |
| APA | Zhang, Y.,Chen, SF.,Ouyang, ZQ.,Hu, J.,Xiong, QH.,...&Jin, CZ.(2000).Stretching and imaging studies of single DNA molecules.CHINESE SCIENCE BULLETIN,45(15),1365. |
| MLA | Zhang, Y,et al."Stretching and imaging studies of single DNA molecules".CHINESE SCIENCE BULLETIN 45.15(2000):1365. |
入库方式： OAI收割
来源：上海应用物理研究所
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