Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B
文献类型：期刊论文
| 作者 | Jia, AQ; Li, X; Tan, NH; Liu, XZ; Shen, YM; Zhou, J
|
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2006-02-01 |
| 卷号 | 49期号:1页码:63-66 |
| 关键词 | Pseudostellaria heterophylla cyclopeptides HB enzymatic cyclization isotope labeled |
| ISSN号 | 1006-9291 |
| 通讯作者 | Zhou, J (reprint author), Grad Univ Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China. jzhou@mail.kib.ac.cn |
| 英文摘要 | The crude enzyme (PH-1) isolated from Pseudostellaria heterophylla by our group has catalyzed enzymatic cyclization of linear peptide NH2-Gly(1)-GlY(2)-Leu-Pro-Pro-Pro-lle-Phe-COOH (4) into cyclopeptide heterophyllin B (HB) from plant for the first time. To ensure this reaction, some analytical methods including TLC, HPLC, MS, NMR, and C-13 labeling were used to prove that the reaction of substrate 4 sharing residue of NH-Phe-Gly-CO was successful. |
| 学科主题 | Chemistry, Multidisciplinary |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000236156000005 |
| 公开日期 | 2012-10-12 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/15430]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Grad Univ Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Peptide Co Ltd, Hangzhou 310018, Peoples R China 3.SW Forestry Coll, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jia, AQ,Li, X,Tan, NH,et al. Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2006,49(1):63-66. |
| APA | Jia, AQ,Li, X,Tan, NH,Liu, XZ,Shen, YM,&Zhou, J.(2006).Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B.SCIENCE IN CHINA SERIES B-CHEMISTRY,49(1),63-66. |
| MLA | Jia, AQ,et al."Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B".SCIENCE IN CHINA SERIES B-CHEMISTRY 49.1(2006):63-66. |
入库方式： OAI收割
来源：昆明植物研究所
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