Ct3d: tracking microglia motility in 3D using a novel cosegmentation approach
文献类型：期刊论文
| 作者 | Du, Jiulin
|
| 刊名 | BIOINFORMATICS
 |
| 出版日期 | 2011 |
| 卷号 | 27期号:4页码:564-571 |
| 关键词 | IN-VIVO FLUORESCENCE MICROSCOPY 2-PHOTON MICROSCOPY ACTIVE CONTOURS CELL TRACKING SEGMENTATION IMAGES ACTIVATION FILTERS |
| ISSN号 | 1367-4803 |
| 通讯作者 | Du, JL (reprint author), Shanghai Inst Biol Sci, Inst Neurosci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China,forestdu@ion.ac.cn ; axel@picb.ac.cn |
| 英文摘要 | Motivation: Cell tracking is an important method to quantitatively analyze time-lapse microscopy data. While numerous methods and tools exist for tracking cells in 2D time-lapse images, only few and very application-specific tracking tools are available for 3D time-lapse images, which is of high relevance in immunoimaging, in particular for studying the motility of microglia in vivo. Results: We introduce a novel algorithm for tracking cells in 3D time-lapse microscopy data, based on computing cosegmentations between component trees representing individual time frames using the so-called tree-assignments. For the first time, our method allows to track microglia in three dimensional confocal time-lapse microscopy images. We also evaluate our method on synthetically generated data, demonstrating that our algorithm is robust even in the presence of different types of inhomogeneous background noise. |
| 学科主题 | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics |
| 收录类别 | SCI |
| 资助信息 | National Basic Research Program of China[2006CB806605]; Key State Research Program of China[2006CB943802]; Shanghai Institutes for Biological Sciences[2009GS-YJ-03] |
| 语种 | 英语 |
| 公开日期 | 2012-07-13 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/1552]  |
| 专题 | 上海神经科学研究所_神经所(总) 上海神经科学研究所_感觉整合与行为研究组 |
| 推荐引用方式 GB/T 7714 | Du, Jiulin. Ct3d: tracking microglia motility in 3D using a novel cosegmentation approach[J]. BIOINFORMATICS,2011,27(4):564-571. |
| APA | Du, Jiulin.(2011).Ct3d: tracking microglia motility in 3D using a novel cosegmentation approach.BIOINFORMATICS,27(4),564-571. |
| MLA | Du, Jiulin."Ct3d: tracking microglia motility in 3D using a novel cosegmentation approach".BIOINFORMATICS 27.4(2011):564-571. |
入库方式： OAI收割
来源：上海神经科学研究所
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