Pitx3-CreER mice showing restricted Cre expression in developing ocular lens and skeletal muscles
文献类型:期刊论文
作者 | Xiong, Zhi-Qi![]() |
刊名 | GENESIS
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出版日期 | 2008 |
卷号 | 46期号:6页码:324-328 |
关键词 | ocular lens skeletal muscles Cre recombinase Pitx3 BAC transgene MIDBRAIN DOPAMINERGIC-NEURONS HOMEOBOX GENE TRANSGENIC MICE APHAKIA MICE PITX3 PROMOTER RECOMBINASE DELETION REGION CELLS |
ISSN号 | 1526-954X |
通讯作者 | Ding, YQ (reprint author), Chinese Acad Sci, Inst Neurosci, 320 Yue Rang Rd, Shanghai 200031, Peoples R China,dingyq@ion.ac.cn |
英文摘要 | To generate temporally controlled inactivation or activation of interested genes in Pitx3-expressing cells, the tamoxifen-inducible form of Cre, CreER(T2), was inserted into the Pitx3 locus of a mouse BAC clone. Following a single dose of tamoxifen, Cre activity in Pitx3-CreER(T2) transgenic mice was observed in the ocular lens and skeletal muscles but not in the central nervous system at various embryonic stages. This mouse line provides a reagent for driving inducible Cre-dependent recombination in the lens and skeletal muscles during embryonic development. |
学科主题 | Developmental Biology ; Genetics & Heredity |
收录类别 | SCI |
语种 | 英语 |
公开日期 | 2012-07-23 |
源URL | [http://ir.sibs.ac.cn/handle/331001/1726] ![]() |
专题 | 上海神经科学研究所_神经所(总) 上海神经科学研究所_疾病神经生物学研究组 |
推荐引用方式 GB/T 7714 | Xiong, Zhi-Qi. Pitx3-CreER mice showing restricted Cre expression in developing ocular lens and skeletal muscles[J]. GENESIS,2008,46(6):324-328. |
APA | Xiong, Zhi-Qi.(2008).Pitx3-CreER mice showing restricted Cre expression in developing ocular lens and skeletal muscles.GENESIS,46(6),324-328. |
MLA | Xiong, Zhi-Qi."Pitx3-CreER mice showing restricted Cre expression in developing ocular lens and skeletal muscles".GENESIS 46.6(2008):324-328. |
入库方式: OAI收割
来源:上海神经科学研究所
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