Transient receptor potential canonical channels in angiogenesis and axon guidance
文献类型：期刊论文
| 作者 | Yu, Peng-chun ; Du, Jiu-lin |
| 刊名 | CELLULAR AND MOLECULAR LIFE SCIENCES
 |
| 出版日期 | 2011 |
| 卷号 | 68期号:23页码:3815-3821 |
| 关键词 | TRPC Calcium Endothelial cells Growth cone Angiogenesis Axon guidance OPERATED CA2+ ENTRY NERVE GROWTH CONES TRP CHANNELS ENDOTHELIAL-CELLS INTRACELLULAR CALCIUM ION CHANNELS IN-VIVO CHEMOTROPIC GUIDANCE SIGNAL-TRANSDUCTION CAPSAICIN RECEPTOR |
| ISSN号 | 1420-682X |
| 通讯作者 | Yu, PC (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Neurosci, Inst Neurosci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China,chunpengyu@ion.ac.cn ; forestdu@ion.ac.cn |
| 英文摘要 | Wiring of vascular and neural networks requires precise guidance of growing blood vessels and axons, respectively, to reach their targets during development. Both of the processes share common molecular signaling pathways. Transient receptor potential canonical (TRPC) channels are calcium-permeable cation channels and gated via receptor- or store-operated mechanisms. Recent studies have revealed the requirement of TRPC channels in mediating guidance cue-induced calcium influx and their essential roles in regulating axon navigation and angiogenesis. Dissecting TRPC functions in these physiological processes may provide therapeutic implications for suppressing pathological angiogenesis and improving nerve regeneration. |
| 学科主题 | Biochemistry & Molecular Biology ; Cell Biology |
| 收录类别 | SCI |
| 资助信息 | National Basic Research Program of China[2011CBA00400, 2006CB806605]; State Key Research Program of China[2006CB943802]; Shanghai government[06dj14010, 07pj14107]; Chinese Academy of Sciences |
| 语种 | 英语 |
| 公开日期 | 2012-07-13 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/1521]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Yu, Peng-chun,Du, Jiu-lin. Transient receptor potential canonical channels in angiogenesis and axon guidance[J]. CELLULAR AND MOLECULAR LIFE SCIENCES,2011,68(23):3815-3821. |
| APA | Yu, Peng-chun,&Du, Jiu-lin.(2011).Transient receptor potential canonical channels in angiogenesis and axon guidance.CELLULAR AND MOLECULAR LIFE SCIENCES,68(23),3815-3821. |
| MLA | Yu, Peng-chun,et al."Transient receptor potential canonical channels in angiogenesis and axon guidance".CELLULAR AND MOLECULAR LIFE SCIENCES 68.23(2011):3815-3821. |
入库方式： OAI收割
来源：上海神经科学研究所
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