Changing Dendritic Field Size of Mouse Retinal Ganglion Cells in Early Postnatal Development
文献类型：期刊论文
| 作者 | Ren, Lei ; Liang, Haitian ; Diao, Ling ; He, Shigang |
| 刊名 | DEVELOPMENTAL NEUROBIOLOGY
 |
| 出版日期 | 2010 |
| 卷号 | 70期号:6页码:397-407 |
| 关键词 | retinal ganglion cells dendritic fields development starburst cells VAChT INNER PLEXIFORM LAYER RABBIT RETINA AMACRINE CELLS QUANTITATIVE-ANALYSIS VERTEBRATE RETINA VISUAL EXPERIENCE MAMMALIAN RETINA ALPHA-GANGLION BIPOLAR CELLS RAT RETINA |
| ISSN号 | 1932-8451 |
| 通讯作者 | He, SG (reprint author), Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China,shiganghe@moon.ibp.ac.cn |
| 英文摘要 | During early postnatal development, dendrites of retinal ganglion cells (RGCs) extend and branch in the inner plexiform layer to establish the adult level of stratification, pattern of branching, and coverage. Many studies have described the branching patterns, transient features, and regulatory factors of stratification of the RGCs. The rate of RGC dendritic field (DF) expansion relative to the growing retina has not been systematically investigated. In this study, we used two methods to examine the relative expansion of RGC DFs. First, we measured the size of RGC DFs and the diameters of the eyeballs at several postnatal stages. We compared the measurements with the RGC DF sizes calculated from difference of the eyeball sizes based on a linear expansion assumption. Second, we used the number of cholinergic amacrine cells (SACs) circum-scribed by the DFs of RGCs at corresponding time points as an internal ruler to assess the size of DFs. We found most RGCs exhibit a phase of faster expansion relative to the retina between postnatal day 8 (P8) and P13, followed by a phase of retraction between P13 and adulthood. The morphological alpha cells showed the faster growing phase but not the retraction phase, whereas the morphological ON-OFF direction selective ganglion cells expanded in the same pace as the growing retina. These findings indicate different RGCs show different modes of growth, whereas most subtypes exhibit a fast expansion followed by a retraction phase to reach the adult size. (C) 2009 Wiley Periodicals. Inc. Develop Neurobiol 70: 397-407.2010 |
| 学科主题 | Developmental Biology ; Neurosciences & Neurology |
| 收录类别 | SCI |
| 资助信息 | NSFC[30530280]; National Basic Research Program of China[200703512208, 2006CB911003] |
| 语种 | 英语 |
| 公开日期 | 2012-07-13 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/1596]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Ren, Lei,Liang, Haitian,Diao, Ling,et al. Changing Dendritic Field Size of Mouse Retinal Ganglion Cells in Early Postnatal Development[J]. DEVELOPMENTAL NEUROBIOLOGY,2010,70(6):397-407. |
| APA | Ren, Lei,Liang, Haitian,Diao, Ling,&He, Shigang.(2010).Changing Dendritic Field Size of Mouse Retinal Ganglion Cells in Early Postnatal Development.DEVELOPMENTAL NEUROBIOLOGY,70(6),397-407. |
| MLA | Ren, Lei,et al."Changing Dendritic Field Size of Mouse Retinal Ganglion Cells in Early Postnatal Development".DEVELOPMENTAL NEUROBIOLOGY 70.6(2010):397-407. |
入库方式： OAI收割
来源：上海神经科学研究所
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