Identification and two-photon imaging of oligodendrocyte in CA1 region of hippocampal slices
文献类型：期刊论文
| 作者 | Zhou, Wei ; Ge, Woo-Ping ; Zeng, Shaoqun ; Duan, Shumin ; Luo, Qingming |
| 刊名 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
 |
| 出版日期 | 2007 |
| 卷号 | 352期号:3页码:598-602 |
| 关键词 | oligodendrocyte whole-cell recording two-photon laser scanning microscopy CA1 region hippocampal slice LONG-TERM POTENTIATION TRANSPORTER CURRENTS GLUTAMATE RELEASE DENDRITIC SPINES NMDA RECEPTORS GLIAL CALCIUM ASTROCYTES SYNAPSES CELLS LTP |
| ISSN号 | 0006-291X |
| 通讯作者 | Luo, QM (reprint author), Huazhong Univ Sci & Technol, Key Lab Biomed Photon, Minist Educ, Wuhan Natl Lab Optoelect, Wuhan 430074, Peoples R China,qluo@mail.hust.edu.cn |
| 英文摘要 | Oligodendrocyte (OL) plays a critical role in myelination and axon maintenance in central nervous system. Recent studies show that OL can also express NMDA receptors in development and pathological situations in white matter. There is still lack of studies about OL properties and function in gray matter of brain. Here we reported that some glial cells in CA1 region of rat hippocampal slices (P15-23) had distinct electrophysiological characteristics from the other glia cells in this region, while they displayed uniform properties with OL from white matter in previous report; therefore, they were considered as OL in hippocampus. By loading dye in recording pipette and imaging with two-photon laser scanning microscopy, we acquired the high spatial resolution, three-dimension images of these special cells in live slices. The OL in hippocampus shows a complex process-bearing shape and the distribution of several processes is parallel to Schaffer fiber in CA1 region. When stimulating Schaffer fiber, OL displays a long duration depolarization mediated by inward rectifier potassium channel. This suggested that the OL in CA1 region could sense the neuronal activity and contribute to potassium clearance. (c) 2006 Elsevier Inc. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology ; Biophysics |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2012-07-23 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/1790]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Zhou, Wei,Ge, Woo-Ping,Zeng, Shaoqun,et al. Identification and two-photon imaging of oligodendrocyte in CA1 region of hippocampal slices[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2007,352(3):598-602. |
| APA | Zhou, Wei,Ge, Woo-Ping,Zeng, Shaoqun,Duan, Shumin,&Luo, Qingming.(2007).Identification and two-photon imaging of oligodendrocyte in CA1 region of hippocampal slices.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,352(3),598-602. |
| MLA | Zhou, Wei,et al."Identification and two-photon imaging of oligodendrocyte in CA1 region of hippocampal slices".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 352.3(2007):598-602. |
入库方式： OAI收割
来源：上海神经科学研究所
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