How does a neuron perform subtraction? - Arithmetic rules of synaptic integration of excitation and inhibition
文献类型：期刊论文
| 作者 | Wang, Xu-Dong ; Hao, Jiang ; Poo, Mu-Ming ; Zhang, Xiao-Hui |
| 刊名 | ADVANCES IN NEURAL NETWORKS - ISNN 2006, PT 1
 |
| 出版日期 | 2006 |
| 卷号 | 3971页码:41104 |
| 关键词 | CA1 PYRAMIDAL NEURONS SUPRALINEAR SUMMATION INPUTS CELLS MODEL |
| ISSN号 | 0302-9743 |
| 通讯作者 | Wang, XD (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Grad Sch, Inst Neurosci, Shanghai 200031, Peoples R China,wxd@ion.ac.cn ; acchj@ion.ac.cn ; mpoo@berkeley.edu ; xhzhang@ion.ac.cn |
| 英文摘要 | Numerous learning rules have been devised to carry out computational tasks in various neural network models. However, the rules for determining how a neuron integrates thousands of synaptic inputs on the dendritic arbors of a realistic neuronal model are still largely unknown. In this study, we investigated the properties of integration of excitatory and inhibitory postsynaptic potentials in a reconstructed pyramidal neuron in the CA1 region of the hippocampus. We found that the integration followed a nonlinear subtraction rule (the Cross-Shunting Rule, or CS rule). Furthermore, the shunting effect is dependent on the spatial location of inhibitory synapses, but not that of excitatory synapses. The shunting effect of inhibitory inputs was also found to promote the synchronization of neuronal firing when the CS rule was applied to a small scale neural network. |
| 学科主题 | Computer Science |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2012-07-23 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/1854]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Wang, Xu-Dong,Hao, Jiang,Poo, Mu-Ming,et al. How does a neuron perform subtraction? - Arithmetic rules of synaptic integration of excitation and inhibition[J]. ADVANCES IN NEURAL NETWORKS - ISNN 2006, PT 1,2006,3971:41104. |
| APA | Wang, Xu-Dong,Hao, Jiang,Poo, Mu-Ming,&Zhang, Xiao-Hui.(2006).How does a neuron perform subtraction? - Arithmetic rules of synaptic integration of excitation and inhibition.ADVANCES IN NEURAL NETWORKS - ISNN 2006, PT 1,3971,41104. |
| MLA | Wang, Xu-Dong,et al."How does a neuron perform subtraction? - Arithmetic rules of synaptic integration of excitation and inhibition".ADVANCES IN NEURAL NETWORKS - ISNN 2006, PT 1 3971(2006):41104. |
入库方式： OAI收割
来源：上海神经科学研究所
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