Amiloride inhibition of glycinergic miniature IPSCs in mechanically dissociated rat spinal neurons
文献类型：期刊论文
| 作者 | Li, Y ; Li, YF ; Xu, TL(徐天乐) |
| 刊名 | NEUROSCIENCE LETTERS
 |
| 出版日期 | 2003 |
| 卷号 | 349期号:1页码:17-20 |
| 关键词 | amiloride transmission glycinergic miniature IPSCs glycine receptor whole-cell recording spinal dorsal horn neurons NA+ CHANNEL ANALOGS RECEPTORS TRANSPORT TOOLS BRAIN |
| ISSN号 | 0304-3940 |
| 通讯作者 | Xu, TL (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Neurosci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China, |
| 英文摘要 | The effect of amiloride on glycinergic transmission in mechanically dissociated rat spinal dorsal horn neurons was examined with the use of whole-cell patch-clamp recording. Amiloride reversibly reduced both the frequency and amplitude of spontaneous glycinergic miniature IPSCs (mIPSCs) and its inhibitory effect on glycinergic rnIPSCs persisted in either Ca2+-free or Na+-free external solutions while it disappeared in K+-free external solution. Analysis of the relationship between rnIPSCs aniplitude and frequency at various holding potentials shows that amiloride inhibition of glycinergic rnIPSC frequency could result indirectly from its inhibition of amplitude. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved. |
| 学科主题 | Neurosciences & Neurology |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2012-07-23 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/2004]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Li, Y,Li, YF,Xu, TL. Amiloride inhibition of glycinergic miniature IPSCs in mechanically dissociated rat spinal neurons[J]. NEUROSCIENCE LETTERS,2003,349(1):17-20. |
| APA | Li, Y,Li, YF,&Xu, TL.(2003).Amiloride inhibition of glycinergic miniature IPSCs in mechanically dissociated rat spinal neurons.NEUROSCIENCE LETTERS,349(1),17-20. |
| MLA | Li, Y,et al."Amiloride inhibition of glycinergic miniature IPSCs in mechanically dissociated rat spinal neurons".NEUROSCIENCE LETTERS 349.1(2003):17-20. |
入库方式： OAI收割
来源：上海神经科学研究所
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