Ultrasensitive electrochemical sensing of the anticancer drug tirapazamine using an ordered mesoporous carbon modified pyrolytic graphite electrode
文献类型：期刊论文
| 作者 | Shao SJ(邵士俊) ; Shao SJ(邵士俊); Guo Y(郭勇)
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| 刊名 | Biosensors and Bioelectronics
 |
| 出版日期 | 2009 |
| 卷号 | 24页码:3391-3394 |
| ISSN号 | 0956-5663 |
| 关键词 | Ordered mesoporous carbon Tirapazamine Electrochemical sensor Ultrasensitive determination |
| 通讯作者 | 邵士俊 |
| 中文摘要 | A new ordered mesoporous carbon (OMC) modified pyrolytic graphite electrode (PGE) was prepared to investigate electrochemical behavior of the anticancer drug tirapazamine (TPZ). Compared to the bare PGE, themodifiedelectrode showedanexcellent electrochemical response to TPZ. The anodic peak current (Ipa) of TPZ at the OMC/PGE is 180-fold higher than that of the bare PGE. The Ipa is proportional with TPZ concentration in the range of 5.0×10−11 to 1.5×10−5 mol L−1. The linear regression equations are Ipa ( A) = 0.0000044 + 16.928CTPZ ( mol L−1), with a detection limit (S/N = 3) of 2.0×10−11 mol L−1. This proposedmethod can be potentially used for ultrasensitive electrochemical sensing of TPZ inphysiological condition. |
| 学科主题 | 分析化学与药物化学 |
| 资助信息 | National Nature Science Foundation of China (No. 20672121) |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000267577900036 |
| 公开日期 | 2012-09-29 |
| 源URL | [http://210.77.64.217/handle/362003/1186]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Shao SJ(邵士俊); Shao SJ(邵士俊) |
| 推荐引用方式 GB/T 7714 | Shao SJ,Shao SJ,Guo Y. Ultrasensitive electrochemical sensing of the anticancer drug tirapazamine using an ordered mesoporous carbon modified pyrolytic graphite electrode[J]. Biosensors and Bioelectronics,2009,24:3391-3394. |
| APA | 邵士俊,邵士俊,&郭勇.(2009).Ultrasensitive electrochemical sensing of the anticancer drug tirapazamine using an ordered mesoporous carbon modified pyrolytic graphite electrode.Biosensors and Bioelectronics,24,3391-3394. |
| MLA | 邵士俊,et al."Ultrasensitive electrochemical sensing of the anticancer drug tirapazamine using an ordered mesoporous carbon modified pyrolytic graphite electrode".Biosensors and Bioelectronics 24(2009):3391-3394. |
入库方式： OAI收割
来源：兰州化学物理研究所
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