Selective determination of L-dopa in the presence of uric acid and ascorbic acid at a gold nanoparticle self-assembled carbon nanotube-modified pyrolytic graphite electrode
文献类型：期刊论文
| 作者 | Shao SJ(邵士俊) ; Wang XL(王晓来); Shao SJ(邵士俊); Guo Y(郭勇)
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| 刊名 | Electrochimica Acta
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| 出版日期 | 2010 |
| 卷号 | 55页码:4711-4716 |
| 关键词 | Gold nanoparticles Carbon nanotubes Self-assembly L-dopa Pyrolytic graphite electrode |
| ISSN号 | 0013-4686 |
| 通讯作者 | 王晓来 ; 邵士俊 |
| 中文摘要 | Gold nanoparticle-functionalized carbon nanotubes (AuNP-CNT) have been prepared by a novel selfassembly method. The new material has been characterized by transmission electron microscopy (TEM) and X-ray diffraction (XRD) and utilized for constructing AuNP-CNT-modified pyrolytic graphite electrode (AuNP-CNT/PGE) to investigate the electrochemical behavior of L-dopa in neutral phosphate buffer solution. Compared to bare PG electrode, AuNP-CNT/PGE shows novel properties towards the electrochemical redox of L-dopa in phosphate buffer solution at pH 7.0. The oxidation potential of L-dopa shows a significant decrease at the AuNP-CNT/PGE. The oxidation current of L-dopa is about 5-fold higher than that of the unmodified PGE. Using differential pulse voltammetry (DPV) method, the oxidation current is well linear with L-dopa concentration in the range of 0.1–150_M, with a detection limit of about 50nM (S/N = 3). The proposed electrode can also effectively avoid the interference of ascorbic acid and uric acid, making the proposed sensor suitable for the accurate determination of L-dopa in both pharmaceutical preparations and human body fluids. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China (No. 20672121);the open fund of State Key Laboratory of Oxo Synthesis & Selective Oxidation (Grant No.OSSO2008kjk6) |
| 语种 | 英语 |
| WOS记录号 | WOS:000278612100006 |
| 公开日期 | 2012-09-29 |
| 源URL | [http://210.77.64.217/handle/362003/1214]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 兰州化学物理研究所_OSSO国家重点实验室 |
| 通讯作者 | Shao SJ(邵士俊); Wang XL(王晓来); Shao SJ(邵士俊) |
| 推荐引用方式 GB/T 7714 | Shao SJ,Wang XL,Shao SJ,et al. Selective determination of L-dopa in the presence of uric acid and ascorbic acid at a gold nanoparticle self-assembled carbon nanotube-modified pyrolytic graphite electrode[J]. Electrochimica Acta,2010,55:4711-4716. |
| APA | 邵士俊,王晓来,邵士俊,&郭勇.(2010).Selective determination of L-dopa in the presence of uric acid and ascorbic acid at a gold nanoparticle self-assembled carbon nanotube-modified pyrolytic graphite electrode.Electrochimica Acta,55,4711-4716. |
| MLA | 邵士俊,et al."Selective determination of L-dopa in the presence of uric acid and ascorbic acid at a gold nanoparticle self-assembled carbon nanotube-modified pyrolytic graphite electrode".Electrochimica Acta 55(2010):4711-4716. |
入库方式： OAI收割
来源：兰州化学物理研究所
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