Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo
文献类型：期刊论文
| 作者 | Shi YP(师彦平) ; Shi YP(师彦平)
|
| 刊名 | Anal Bioanal Chem
 |
| 出版日期 | 2006 |
| 卷号 | 384页码:939-945 |
| 关键词 | Enantiomer separation Polysaccharide carbamate phase Specific rotation Circular dichroism Tetrahydropalmatine Tetrahydroberberine |
| ISSN号 | 1618-2642 |
| 通讯作者 | 师彦平 |
| 中文摘要 | HPLC methods have been developed for chiral resolution of the enantiomers of dl-tetrahydropalmatine (THP) and dl-tetrahydroberberine (THB), two active constituents of Corydalis yanhusuo W.T. Wang. On the analytical scale, good baseline separation of the enantiomers was achieved using cellulose tris(3,5-dimethylphenylcarbamate) chiral stationary phases in both normal-phase and polar organic modes. Validation of the analytical methods, including linearity, limits of detection, recovery, and precision, and semipreparative resolution of dl-THP and dl-THB, were achieved with methanol as mobile phase, without any basic additives, in polar organic mode using cellulose tris (3,5-dimethylphenylcarbamate) chiral stationary phases. On the semipreparative scale, small quantities of the individual enantiomers of THP and THB were isolated for study of the chiroptical properties of the individual enantiomers. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | the “Bairen Jihua” Foundation of Chinese Academy of Sciences (CAS) in 2000;the National Natural Science Foundation of China (NSFC No.20475057) |
| 语种 | 英语 |
| WOS记录号 | WOS:000236031500012 |
| 公开日期 | 2012-10-14 |
| 源URL | [http://210.77.64.217/handle/362003/1448]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Shi YP(师彦平); Shi YP(师彦平) |
| 推荐引用方式 GB/T 7714 | Shi YP,Shi YP. Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo[J]. Anal Bioanal Chem,2006,384:939-945. |
| APA | 师彦平,&师彦平.(2006).Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo.Anal Bioanal Chem,384,939-945. |
| MLA | 师彦平,et al."Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo".Anal Bioanal Chem 384(2006):939-945. |
入库方式： OAI收割
来源：兰州化学物理研究所
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