Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra
文献类型：期刊论文
| 作者 | Zhou, Yan ; Huang, Sheng-Xiong ; Pu, Jian-Xin ; Li, Jin-Rong ; Ding, Li-Sheng ; Chen, Dao-Feng ; Sun, Han-Dong ; Xu, Hong-Xi |
| 刊名 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
 |
| 出版日期 | 2011 |
| 卷号 | 56期号:5页码:916-927 |
| 关键词 | Schisandra species Nortriterpenoids Lignans Ultra performance liquid chromatography Quadrupole time-of-flight mass spectrometry |
| ISSN号 | 0731-7085 |
| 产权排序 | 1 |
| 通讯作者 | Sun, Han-Dong ; Xu, Hong-Xi |
| 英文摘要 | An ultra performance liquid chromatography (UPLC) coupled with quadrupole time-of-flight mass spectrometry (QTOF-MS) procedure is designed for the first simultaneous analysis of nortriterpenoids and lignans in Schisandra samples. The method consists of three individual mass spectrometric experiments, including the full scan MS, MS/MS experiment and in-source collision induced dissociation (CID) MS/MS, which enable the identification of diagnostic fragmentation pathways of nortriterpenoids and lignans. As such, a total of 6 nortriterpenoids and 10 lignans were unequivocally identified, and one nortriterpenoid and 20 lignans were tentatively identified from different Schisandra samples within 12.5 min. In addition, 6 nortriterpenoids and 10 lignans were quantified in 48 samples of S. chinensis and S. sphenanthera using an extract ion chromatogram (XIC) of the full scan MS experiment. Dataset obtained from UPLC-MS was processed with principal component analysis (PCA) and orthogonal partial least squared discriminant analysis (OPLS-DA) to compare the difference between the two Schisandra species. (C) 2011 Elsevier B.V. All rights reserved. |
| 学科主题 | Chemistry; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China[30830115, 30973634, 21072185]; Chinese Academy of Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000295304100009 |
| 公开日期 | 2012-11-09 |
| 源URL | [http://210.75.237.14/handle/351003/23514]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Zhou, Yan,Huang, Sheng-Xiong,Pu, Jian-Xin,et al. Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2011,56(5):916-927. |
| APA | Zhou, Yan.,Huang, Sheng-Xiong.,Pu, Jian-Xin.,Li, Jin-Rong.,Ding, Li-Sheng.,...&Xu, Hong-Xi.(2011).Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,56(5),916-927. |
| MLA | Zhou, Yan,et al."Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 56.5(2011):916-927. |
入库方式： OAI收割
来源：成都生物研究所
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