Enantioselective 1,6-Michael addition of anthrone to 3-methyl-4-nitro-5-alkenyl-isoxazoles catalyzed by bifunctional thiourea-tertiary amines
文献类型：期刊论文
| 作者 | Sun, Hong-Wei ; Liao, Yu-Hua ; Wu, Zhi-Jun ; Wang, Hao-Yu ; Zhang, Xiao-Mei ; Yuan, Wei-Cheng |
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2011 |
| 卷号 | 67期号:22页码:3991-3996 |
| 关键词 | Asymmetric catalysis Michael addition Organocatalysis Anthrone Isoxazole |
| ISSN号 | 0040-4020 |
| 产权排序 | 2 |
| 通讯作者 | Yuan, WC (reprint author), Chinese Acad Sci, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China. |
| 英文摘要 | A simple and efficient method for the enantioselective 1,6-Michael addition reaction of anthrone to a series of 3-methyl-4-nitro-5-alkenyl-isoxazoles with a bifunctional thiourea-tertiary amine as catalyst is described. This transformation proceeds smoothly with 10 mol % catalyst and provides a series of Michael adducts bearing 3-methyl-4-nitro-isoxazole and anthrone units with good to high enantioselectivities (up to 96% ee) and in very high yields (up to 99%). (C) 2011 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China[20802074]; National Basic Research Program of China (973 Program)[2010CB833300] |
| 语种 | 英语 |
| WOS记录号 | WOS:000291140100004 |
| 公开日期 | 2012-11-09 |
| 源URL | [http://210.75.237.14/handle/351003/23544]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Sun, Hong-Wei,Liao, Yu-Hua,Wu, Zhi-Jun,et al. Enantioselective 1,6-Michael addition of anthrone to 3-methyl-4-nitro-5-alkenyl-isoxazoles catalyzed by bifunctional thiourea-tertiary amines[J]. TETRAHEDRON,2011,67(22):3991-3996. |
| APA | Sun, Hong-Wei,Liao, Yu-Hua,Wu, Zhi-Jun,Wang, Hao-Yu,Zhang, Xiao-Mei,&Yuan, Wei-Cheng.(2011).Enantioselective 1,6-Michael addition of anthrone to 3-methyl-4-nitro-5-alkenyl-isoxazoles catalyzed by bifunctional thiourea-tertiary amines.TETRAHEDRON,67(22),3991-3996. |
| MLA | Sun, Hong-Wei,et al."Enantioselective 1,6-Michael addition of anthrone to 3-methyl-4-nitro-5-alkenyl-isoxazoles catalyzed by bifunctional thiourea-tertiary amines".TETRAHEDRON 67.22(2011):3991-3996. |
入库方式： OAI收割
来源：成都生物研究所
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