Encapsulation studies and selective membrane permeability properties of self-assembly hollow nanospheres
文献类型：期刊论文
| 作者 | Ha, Wei ; Meng, Xian-Wei ; Li, Quan ; Fan, Min-Min ; Peng, Shu-Lin ; Ding, Li-Sheng ; Tian, Xuan ; Zhang, Sheng ; Li, Bang-Jing |
| 刊名 | SOFT MATTER
 |
| 出版日期 | 2011 |
| 卷号 | 7期号:3页码:1018-1024 |
| ISSN号 | 1744-683X |
| 产权排序 | 1 |
| 通讯作者 | Zhang, Sheng ; Li, Bang-Jing |
| 英文摘要 | This paper presents a kind of self-assembled hollow nanosphere for enzyme encapsulation. The enzyme molecules were encapsulated in hollow spheres directly in aqueous solution through the self-assembly of rod-coil Alg-g-PEG and alpha-CDs complexes. These Alg-g-PEG/alpha-CD hollow spheres showed semi-permeability which could prevent big enzyme molecules from leaving while allowing small substrates and products to pass through to maintain the enzyme activity. The permeability properties of Alg-g-PEG/alpha-CD hollow nanospheres were investigated by encapsulating different probes. The results showed that the molar mass cutoff (MMCO) of these hollow nanospheres was between 20 and 40 kDa. The encapsulation capability of Alg-g-PEG/alpha-CD hollow nanospheres was also investigated, the results indicated a maximal values for L-asparaginase encapsulation. Furthermore, the encapsulation behavior for L-asparaginase showed PEG graft density (GD) dependence. |
| 学科主题 | Chemistry; Materials Science; Physics; Polymer Science |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China (NSFC)[21074138, 51073107, 50703025]; State Key Laboratory of Polymer Materials Engineering (Sichuan University)[KF201003] |
| 语种 | 英语 |
| WOS记录号 | WOS:000286615500031 |
| 公开日期 | 2012-11-09 |
| 源URL | [http://210.75.237.14/handle/351003/23579]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Ha, Wei,Meng, Xian-Wei,Li, Quan,et al. Encapsulation studies and selective membrane permeability properties of self-assembly hollow nanospheres[J]. SOFT MATTER,2011,7(3):1018-1024. |
| APA | Ha, Wei.,Meng, Xian-Wei.,Li, Quan.,Fan, Min-Min.,Peng, Shu-Lin.,...&Li, Bang-Jing.(2011).Encapsulation studies and selective membrane permeability properties of self-assembly hollow nanospheres.SOFT MATTER,7(3),1018-1024. |
| MLA | Ha, Wei,et al."Encapsulation studies and selective membrane permeability properties of self-assembly hollow nanospheres".SOFT MATTER 7.3(2011):1018-1024. |
入库方式： OAI收割
来源：成都生物研究所
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