Modular chiral bidentate phosphonites: Design, synthesis, and application in catalytic asymmetric hydroformylation reactions
文献类型：期刊论文
| 作者 | Xia CG(夏春谷)
|
| 刊名 | Chem. Eur. J.
 |
| 出版日期 | 2008 |
| 卷号 | 14页码:7847-7857 |
| 关键词 | asymmetric catalysis bidentate ligands hydroformylation phosphonite ligands rhodium |
| ISSN号 | 0937-6539 |
| 通讯作者 | 夏春谷 ; 丁奎岭 |
| 中文摘要 | A new class of C2-symmetric chiral bidentate phosphonite ligands has been synthesized in moderate to good yields from readily available starting materials. Application of these air-stable chiral phosphonites in the RhI-catalyzed asymmetric hydroformylation of styrene derivatives, vinyl acetate, and allyl cyanide afforded the corresponding chiral aldehydes with high regio- and enantioselectivities under mild reaction conditions. The modular nature of the ligands allows fine-tuning of the selectivities through judicious modifications of the substituents on the ligand backbone. X-ray structural analysis of the catalyst precursor suggested that the steric hindrance caused by the protruding remote substituents of the ligands into the vicinity of the metal center might be an important factor for the enantio-control of the reaction, whereas the sense of asymmetric induction can be rationalized on the basis of a trigonal-bipyramidal transition state diagram. |
| 学科主题 | 清洁催化与生物转化 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (No. 20532050;20632060);the Chinese Academy of Sciences;the Major Basic Research Development Program of China (Grant No.2006CB806106);the Science and Technology Commission of Shanghai Municipality;Merck Research Laboratories |
| 语种 | 英语 |
| WOS记录号 | WOS:000259523500016 |
| 公开日期 | 2012-11-09 |
| 源URL | [http://210.77.64.217/handle/362003/1966]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 通讯作者 | Xia CG(夏春谷) |
| 推荐引用方式 GB/T 7714 | Xia CG. Modular chiral bidentate phosphonites: Design, synthesis, and application in catalytic asymmetric hydroformylation reactions[J]. Chem. Eur. J.,2008,14:7847-7857. |
| APA | 夏春谷.(2008).Modular chiral bidentate phosphonites: Design, synthesis, and application in catalytic asymmetric hydroformylation reactions.Chem. Eur. J.,14,7847-7857. |
| MLA | 夏春谷."Modular chiral bidentate phosphonites: Design, synthesis, and application in catalytic asymmetric hydroformylation reactions".Chem. Eur. J. 14(2008):7847-7857. |
入库方式： OAI收割
来源：兰州化学物理研究所
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