Homogeneous silicone modified primary amine-Brønsted sted acid salt catalyzed aldol reaction: unexpected synergistic effect of polysiloxane with remarkable improvement of efficiency and stereoselectivity
文献类型：期刊论文
| 作者 | Xu LW(徐利文) ; Ju YD(鞠亚东) ; Li L(李莉) ; Qiu HY(邱化玉) ; Jiang JX(蒋剑雄) ; Lai GQ(来国桥) |
| 刊名 | Tetrahedron Letters
 |
| 出版日期 | 2008 |
| 卷号 | 49页码:7037-7041 |
| 关键词 | Enamine catalysis Primary amine Aldol reaction Polysiloxane Organocatalysis |
| ISSN号 | 0040-4039 |
| 通讯作者 | 徐利文 ; 来国桥 |
| 中文摘要 | We have developed a new strategy to improve the stereoselectivity in enamine catalysis by the introduction of super-hydrophobic long-chain silicone/polysiloxane as support/functional group for a model aldol reaction. The homogeneous direct aldol reaction of cyclic ketones with different aromatic aldehydes catalyzed by polysiloxane-derived primary amines has been reported with high yields, good diastereoselectivity, and up to 99% ee. |
| 学科主题 | 物理化学 |
| 收录类别 | SCI |
| 资助信息 | Hangzhou Normal University;the National Nature Science Foundation of China (Project No. 20572114) |
| 语种 | 英语 |
| 公开日期 | 2012-11-09 |
| 源URL | [http://210.77.64.217/handle/362003/1980]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Xu LW,Ju YD,Li L,et al. Homogeneous silicone modified primary amine-Brønsted sted acid salt catalyzed aldol reaction: unexpected synergistic effect of polysiloxane with remarkable improvement of efficiency and stereoselectivity[J]. Tetrahedron Letters,2008,49:7037-7041. |
| APA | 徐利文,鞠亚东,李莉,邱化玉,蒋剑雄,&来国桥.(2008).Homogeneous silicone modified primary amine-Brønsted sted acid salt catalyzed aldol reaction: unexpected synergistic effect of polysiloxane with remarkable improvement of efficiency and stereoselectivity.Tetrahedron Letters,49,7037-7041. |
| MLA | 徐利文,et al."Homogeneous silicone modified primary amine-Brønsted sted acid salt catalyzed aldol reaction: unexpected synergistic effect of polysiloxane with remarkable improvement of efficiency and stereoselectivity".Tetrahedron Letters 49(2008):7037-7041. |
入库方式： OAI收割
来源：兰州化学物理研究所
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