Molecularly imprinted polymer microspheres for solid-phase extraction of protocatechuic acid in Rhizoma homalomenae
文献类型：期刊论文
| 作者 | Shi YP(师彦平) ; Shi YP(师彦平)
|
| 刊名 | Journal of Separation Science
 |
| 出版日期 | 2011 |
| 卷号 | 34页码:2602-2610 |
| 关键词 | Molecularly imprinted polymers Phenolic acids Precipitation polymerization SPE Traditional Chinese medicines |
| ISSN号 | 1615-9306 |
| 通讯作者 | 师彦平 |
| 中文摘要 | Molecularly imprinted polymers (MIPs) had been prepared by precipitation polymerization method using acrylamide as the functional monomer, ethylene glycol dimethacrylate as the cross-linker, acetonitrile as the porogen solvent and protocatechuic acid (PA), one of phenolic acids, as the template molecule. The MIPs were characterized by scanning electron microscopy and Fourier transform infrared, and their performance relative to non-imprinted polymers was assessed by equilibrium binding experiments. Six structurally similar phenolic acids, including p-hydroxybenzoic acid, gallic acid, salicylic acid, syringic acid, vanillic acid, ferulic acid were selected to assess the selectivity and recognition capability of the MIPs. The MIPs were applied to extract PA from the traditional Chinese medicines as a solid-phase extraction sorbent. The resultant cartridge showed that the MIPs have a good extraction performance and were able to selectively extract almost 82% of PA from the extract of Rhizoma homalomenae. Thus, the proposed molecularly imprinted-solid phase extraction-high performance liquid chromatography method can be successfully used to extract and analyse PA in traditional Chinese medicines. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China (No. 21075127;20875095) |
| 语种 | 英语 |
| WOS记录号 | WOS:000296141200007 |
| 公开日期 | 2012-10-18 |
| 源URL | [http://210.77.64.217/handle/362003/1520]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Shi YP(师彦平); Shi YP(师彦平) |
| 推荐引用方式 GB/T 7714 | Shi YP,Shi YP. Molecularly imprinted polymer microspheres for solid-phase extraction of protocatechuic acid in Rhizoma homalomenae[J]. Journal of Separation Science,2011,34:2602-2610. |
| APA | 师彦平,&师彦平.(2011).Molecularly imprinted polymer microspheres for solid-phase extraction of protocatechuic acid in Rhizoma homalomenae.Journal of Separation Science,34,2602-2610. |
| MLA | 师彦平,et al."Molecularly imprinted polymer microspheres for solid-phase extraction of protocatechuic acid in Rhizoma homalomenae".Journal of Separation Science 34(2011):2602-2610. |
入库方式： OAI收割
来源：兰州化学物理研究所
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