中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans

文献类型:期刊论文

作者Xu, You-Kai1; Liao, Shang-Gao2; Na, Zhi3; Hu, Hua-Bin1; Li, Yan4; Luo, Huai-Rong4
刊名FITOTERAPIA
出版日期2012-09-01
卷号83期号:6页码:1120-1124
关键词Gelsemium elegant 21-(2-Oxopropyl)-koumine 11-Methoxygelselegine Immunosuppressive activity
ISSN号0367-326X
通讯作者Xu, YK (reprint author), Chinese Acad Sci, Xishuangbanna Trop Bot Garden, CAS Key Lab Trop Forest Ecol, Mengla 666303, Yunnan Province, Peoples R China.,xyk@xtbg.ac.cn ; lshangg@163.com
英文摘要Bioassay-guided isolation of the stems of Gelsemium elegans has led to the isolation of two new Gelsemium alkaloids, 21-(2-oxopropyl)-koumine (1) and 11-methoxygelselegine (2), and two known alkaloids, koumine (3) and gelselegine (4). The structures of 1-2 were determined by spectroscopic (for both) and single-crystal X-ray diffraction (for 1) analysis. All compounds isolated were evaluated for their potential as immunosuppressive agents and the data suggested that Gelsemium alkaloids of different structural types possibly have potential as immunosuppressive agents. (C) 2012 Elsevier B.V. All rights reserved.
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]OXINDOLE ALKALOIDS ; INDOLE ALKALOIDS
收录类别SCI
资助信息key project of the Tropical Characteristic Medical Resources Branch Research Centre of the Chinese Academy of Sciences [KSCX2-YW-R-172]
语种英语
WOS记录号WOS:000308116600024
公开日期2012-11-30
源URL[http://ir.kib.ac.cn:8080/handle/151853/15708]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Xishuangbanna Trop Bot Garden, CAS Key Lab Trop Forest Ecol, Mengla 666303, Yunnan Province, Peoples R China
2.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Peoples R China
3.Chinese Acad Sci, Lab Trop Plant Resource Sci, Xishuangbanna Trop Bot Garden, Mengla 666303, Yunnan Province, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Xu, You-Kai,Liao, Shang-Gao,Na, Zhi,et al. Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans[J]. FITOTERAPIA,2012,83(6):1120-1124.
APA Xu, You-Kai,Liao, Shang-Gao,Na, Zhi,Hu, Hua-Bin,Li, Yan,&Luo, Huai-Rong.(2012).Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans.FITOTERAPIA,83(6),1120-1124.
MLA Xu, You-Kai,et al."Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans".FITOTERAPIA 83.6(2012):1120-1124.

入库方式: OAI收割

来源:昆明植物研究所

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