Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum
文献类型：期刊论文
| 作者 | Cao, Mingming1,2; Zhang, Yu1 ; He, Hongping1; Li, Shifei1,2; Huang, Shendian1,2; Chen, Duozhi1,2; Tang, Guihua1,2; Li, Shunlin1; Di, Yingtong1; Hao, Xiaojiang1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2012-06-01 |
| 卷号 | 75期号:6页码:1076-1082 |
| ISSN号 | 0163-3864 |
| 关键词 | SKELETON CASCADE HUMILE ASSAY MIQ |
| 英文摘要 | Ten new yuzurine-type Daphniphyllum alkaloids, daphmacromines A-J (1-10), along with seven known alkaloids were isolated from the leaves and stems of Daphniphyllum macropodum. Their structures were elucidated by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry, and the structure of 1 was confirmed by single-crystal X-ray diffraction. The pesticidal and cytotoxic activities of the isolated alkaloids were evaluated in vitro against brine shrimp (Artemia sauna) and five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480), respectively. This study also suggested structural revisions of oxodaphnigracine, oxodaphnigraciline, and epioxodaphnigraciline. |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | SKELETON ; CASCADE ; HUMILE ; ASSAY ; MIQ |
| 资助信息 | National Natural Science Foundation of China [30830114, 31100259]; National Basic Research Program of China (973 Program) [2009CB522303, 2009CB940900]; Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047] |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000305503500011 |
| 公开日期 | 2012-11-30 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/15762]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Mingming,Zhang, Yu,He, Hongping,et al. Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(6):1076-1082. |
| APA | Cao, Mingming.,Zhang, Yu.,He, Hongping.,Li, Shifei.,Huang, Shendian.,...&Hao, Xiaojiang.(2012).Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum.JOURNAL OF NATURAL PRODUCTS,75(6),1076-1082. |
| MLA | Cao, Mingming,et al."Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum".JOURNAL OF NATURAL PRODUCTS 75.6(2012):1076-1082. |
入库方式： OAI收割
来源：昆明植物研究所
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