The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film
文献类型:期刊论文
作者 | Zhang JY(张俊彦)![]() ![]() |
刊名 | Applied Surface Science
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出版日期 | 2011 |
卷号 | 257页码:6429-6434 |
关键词 | Copolymer Thin film Ti6Al4V Cytocompatibility Osteoblast |
ISSN号 | 0169-4332 |
通讯作者 | 刘斌 ; 张俊彦 |
中文摘要 | The objective of the present study is to preliminarily explore the effect of surface chemistry modifica- tion of Ti6Al4V with a fluorine-contained copolymer thin film on the cellular behavior of osteoblasts. A fluorine-contained random copolymer thin film was fabricated on Ti6Al4V substrate, and then char- acterized by X-ray photoelectron spectroscopy (XPS), contact angle meter and surface profiler. The results showed that the surfacemodification of Ti6Al4V alloy could simultaneously transformthe surface chemical constitution and reduce the surface energy evidently. However, the surface morphology and roughness of the Ti6Al4V substrate were hardly changed after the modification. By immersion process with simulated body fluid (SBF) and then by in vitro cytotoxicity test with MC3T3-E1 osteoblasts, the fluorine-contained copolymer thin filmexhibited desirable stability and admirable cytocompatibility. In conclusion, the fluorine-contained copolymer thin filmcould be easily applied inmodifying various solid surfaces, and the as-fabricated film also has potential applications in biomedical field. |
学科主题 | 材料科学与物理化学 |
收录类别 | SCI |
资助信息 | the NationalNatural Science Foundation of China (grant nos. 50823008;20673131);“Hundreds Talent Program” of Chinese Academy of Sciences |
语种 | 英语 |
公开日期 | 2012-12-03 |
源URL | [http://210.77.64.217/handle/362003/2328] ![]() |
专题 | 兰州化学物理研究所_固体润滑国家重点实验室 |
通讯作者 | Zhang JY(张俊彦); Zhang JY(张俊彦) |
推荐引用方式 GB/T 7714 | Zhang JY,Zhang JY. The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film[J]. Applied Surface Science,2011,257:6429-6434. |
APA | 张俊彦,&张俊彦.(2011).The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film.Applied Surface Science,257,6429-6434. |
MLA | 张俊彦,et al."The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film".Applied Surface Science 257(2011):6429-6434. |
入库方式: OAI收割
来源:兰州化学物理研究所
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