Chemical transformations of mackinazolinone and its derivatives
文献类型：期刊论文
| 作者 | Nasrullaev A. O.; Turdibaev Zh E.; Elmuradov B. Zh; Yili A. ; Aisa H. A.; Shakhidoyatov Kh M.
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| 刊名 | CHEMISTRY OF NATURAL COMPOUNDS
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| 出版日期 | 2012 |
| 卷号 | 48期号:4页码:638-642 |
| 关键词 | mackinazolinone mackinazolinthione nucleophilic substitution electrophilic addition |
| ISSN号 | 0009-3130 |
| 英文摘要 | The thioanalog of mackinazolinone (2,3,4,10-tetrahydro-1 H-pyrido2,1-bquinazolin-10-one) was synthesized for the first time by reacting it with P2S5. The thioanalog was reacted with aromatic aldehydes and Vilsmeier- Haack reagent (DMF + POCl3) to produce 4-arylidene- and -hydroxymethylidenemackinazolinthiones, respectively. The reactions of 4-hydroxymethylidenemackinazolinone with isomeric aminophenols and aminobenzoic acids and of hydroxymethylidenemackinazolinthione with thionylchloride were studied. Subsequent reaction of the obtained 4-chloromethylidene derivative with sodium hydroselenide was synthesized a new Se-containing derivative of mackinazolinone. It was shown that 4-formylmackinazolinthione existed in the enol form whereas 4-formylmackinazolinone existed as the enaminoaldehyde tautomer. |
| 学科主题 | Pharmacology & Pharmacy ; Chemistry |
| 收录类别 | SCI |
| WOS记录号 | WOS:000309471600030 |
| 公开日期 | 2012-11-29 |
| 源URL | [http://ir.xjipc.cas.cn/handle/365002/1610]  |
| 专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
| 作者单位 | Uzbek Acad Sci, S Yu Yunusov Inst Chem Plant Subst, Tashkent 700135, Uzbekistan;Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Xinjiang Indigenous Med Plants Resource U, Urumqi 830011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Nasrullaev A. O.,Turdibaev Zh E.,Elmuradov B. Zh,et al. Chemical transformations of mackinazolinone and its derivatives[J]. CHEMISTRY OF NATURAL COMPOUNDS,2012,48(4):638-642. |
| APA | Nasrullaev A. O.,Turdibaev Zh E.,Elmuradov B. Zh,Yili A.,Aisa H. A.,&Shakhidoyatov Kh M..(2012).Chemical transformations of mackinazolinone and its derivatives.CHEMISTRY OF NATURAL COMPOUNDS,48(4),638-642. |
| MLA | Nasrullaev A. O.,et al."Chemical transformations of mackinazolinone and its derivatives".CHEMISTRY OF NATURAL COMPOUNDS 48.4(2012):638-642. |
入库方式： OAI收割
来源：新疆理化技术研究所
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