Chemical Composition, Antimicrobial and Antitumor Activities of the Essential Oils and Crude Extracts of Euphorbia macrorrhiza
文献类型：期刊论文
| 作者 | Lin Jianbo; Dou Jun; Xu Jiangling; Aisa Haji Akber; Aisa, HA
|
| 刊名 | MOLECULES
 |
| 出版日期 | 2012 |
| 卷号 | 17期号:5页码:5030-5039 |
| 关键词 | Euphorbia macrorrhiza essential oil composition antimicrobial activity antitumor activity |
| ISSN号 | 1420-3049 |
| 通讯作者 | Aisa, HA |
| 英文摘要 | The present study aimed to examine the chemical composition and biological activity of essential oils extracted from Euphorbia macrorrhiza collected from Northwest China. The major constituents of the essential oils of aerial parts and roots of E. macrorrhiza are acorenone B (16.72% and 25.80%), (+)-cycloisosativene (14.94% and 12.40%), 3a-hydroxy-5b-androstane (10.62% and 5.52%), copaene (7.37% and 6.29%), l-calamenene (4.13% and 4.65%) and beta-cedrene (8.40% and 7.98%), respectively. The minor components of them are thymene, gamma- terpinene, thymecamphor, alpha-cedrene, zingiberene, trans-caryophyllene, beta- chamigrene, curcumene, pentadecane, (-)-alpha-muurolene, cuparene, gamma-cadinene, (Z)-3-heptadecene, 1,3,7,7-tetramethyl-2-oxabicyclo(4.4.0)dec-5-en-4-one, hexahydrofarnesyl acetone, gamma- elixene and palmitinic acid. The antimicrobial and antitumor activitiy of the E. macrorrhiza essential oil against Staphyloccocus aureus, Escherichia coli, Canidia Albicans and Caco-2 cells were evaluated. Among all the tested microorganisms and Caco-2 cells, the essential oils showed the strongest inhibitory effect on Staphyloccocus aureus (MIC = 2.8 mu g/mL) and Caco-2 cell (IC50 = 11.86 mu g/mL), whereas no effect on Escherichia coli and Candida albicans. The data of this study suggested that the E. macrorrhiza essential oils have great potential as a natural medicine for microbial infections and cancers. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| WOS记录号 | WOS:000304587600022 |
| 公开日期 | 2012-11-29 |
| 源URL | [http://ir.xjipc.cas.cn/handle/365002/1628]  |
| 专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 |
| 通讯作者 | Aisa, HA |
| 作者单位 | Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Chem Plant Resources Arid Reg, Urumqi 830011, Peoples R China;Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin Jianbo,Dou Jun,Xu Jiangling,et al. Chemical Composition, Antimicrobial and Antitumor Activities of the Essential Oils and Crude Extracts of Euphorbia macrorrhiza[J]. MOLECULES,2012,17(5):5030-5039. |
| APA | Lin Jianbo,Dou Jun,Xu Jiangling,Aisa Haji Akber,&Aisa, HA.(2012).Chemical Composition, Antimicrobial and Antitumor Activities of the Essential Oils and Crude Extracts of Euphorbia macrorrhiza.MOLECULES,17(5),5030-5039. |
| MLA | Lin Jianbo,et al."Chemical Composition, Antimicrobial and Antitumor Activities of the Essential Oils and Crude Extracts of Euphorbia macrorrhiza".MOLECULES 17.5(2012):5030-5039. |
入库方式： OAI收割
来源：新疆理化技术研究所
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