中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 计算技术研究所
  3. 中国科学院计算技术研究所
  4. 中国科学院计算技术研究所期刊论文
  5. 英文
热门
NONCODEV5: a comprehensive annotation database for long non-coding RNAs

文献类型：期刊论文

作者Fang, ShuangSang2,3; Zhang, LiLi3,4; Guo, JinCheng2,5; Niu, YiWei3,4; Wu, Yang2; Li, Hui2; Zhao, Lian He2,3; Li, Xi Yuan2; Teng, Xue Yi3,4; Sun, XianHui3,4
刊名NUCLEIC ACIDS RESEARCH
出版日期2018-01-04
卷号46期号:D1页码:D308-D314
ISSN号0305-1048
DOI10.1093/nar/gkx1107
英文摘要NONCODE (http://www.bioinfo.org/noncode) is a systematic database that is dedicated to presenting the most complete collection and annotation of non-coding RNAs (ncRNAs), especially long non-coding RNAs (lncRNAs). Since NONCODE 2016 was released two years ago, the amount of novel identified ncRNAs has been enlarged by the reduced cost of next-generation sequencing, which has produced an explosion of newly identified data. The third-generation sequencing revolution has also offered longer and more accurate annotations. Moreover, accumulating evidence confirmed by biological experiments has provided more comprehensive knowledge of lncRNA functions. The ncRNA data set was expanded by collecting newly identified ncRNAs from literature published over the past two years and integration of the latest versions of RefSeq and Ensembl. Additionally, pig was included in the database for the first time, bringing the total number of species to 17. The number of lncRNAs in NONCODEv5 increased from 527 336 to 548 640. NONCODEv5 also introduced three important new features: (i) human lncRNA-disease relationships and single nucleotide polymorphism-lncRNA-disease relationships were constructed; (ii) human exosome lncRNA expression profiles were displayed; (iii) the RNA secondary structures of NONCODE human transcripts were predicted. NONCODEv5 is also accessible through http://www.noncode.org/.
资助项目National Natural Science Foundation of China[31371320] ; National Natural Science Foundation of China[31401119] ; National Natural Science Foundation of China[31501066] ; National Science Foundation for Young Scholars[31701141] ; National Science Foundation for Young Scholars[31701149]
WOS研究方向Biochemistry & Molecular Biology
语种英语
WOS记录号WOS:000419550700047
出版者OXFORD UNIV PRESS
源URL[http://119.78.100.204/handle/2XEOYT63/6260]  
专题中国科学院计算技术研究所期刊论文_英文
通讯作者Chen, RunSheng; Zhao, Yi
作者单位1.Tsinghua Univ, Sch Med, Ctr Synthet & Syst Biol,TNLIST Dept Automat, MOE Key Lab Bioinformat & Bioinformat Div, Beijing 100084, Peoples R China
2.Chinese Acad Sci, Inst Comp Technol, Adv Comp Res Ctr, Key Lab Intelligent Informat Proc, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Chinese Acad Sci, Inst Biophys, CAS Key Lab RNA Biol, Beijing 100101, Peoples R China
5.Shantou Univ, Med Coll, Dept Biochem & Mol Biol, Shantou 515041, Peoples R China
6.Chinese Acad Sci, Inst Comp Technol, LuoYang Branch, Luoyang, Peoples R China
推荐引用方式
GB/T 7714		 Fang, ShuangSang,Zhang, LiLi,Guo, JinCheng,et al. NONCODEV5: a comprehensive annotation database for long non-coding RNAs[J]. NUCLEIC ACIDS RESEARCH,2018,46(D1):D308-D314.
APA Fang, ShuangSang.,Zhang, LiLi.,Guo, JinCheng.,Niu, YiWei.,Wu, Yang.,...&Zhao, Yi.(2018).NONCODEV5: a comprehensive annotation database for long non-coding RNAs.NUCLEIC ACIDS RESEARCH,46(D1),D308-D314.
MLA Fang, ShuangSang,et al."NONCODEV5: a comprehensive annotation database for long non-coding RNAs".NUCLEIC ACIDS RESEARCH 46.D1(2018):D308-D314.

入库方式： OAI收割

来源：计算技术研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。