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ZOOM! Zillions of oligos mapped
文献类型：期刊论文
| 作者 | Lin, Hao2; Zhang, Zefeng2; Zhang, Michael Q.3; Ma, Bin1; Li, Ming4 |
| 刊名 | BIOINFORMATICS
 |
| 出版日期 | 2008-11-01 |
| 卷号 | 24期号:21页码:2431-2437 |
| ISSN号 | 1367-4803 |
| DOI | 10.1093/bioinformatics/btn416 |
| 英文摘要 | Motivation: The next generation sequencing technologies are generating billions of short reads daily. Resequencing and personalized medicine need much faster software to map these deep sequencing reads to a reference genome, to identify SNPs or rare transcripts. Results: We present a framework for how full sensitivity mapping can be done in the most efficient way, via spaced seeds. Using the framework, we have developed software called ZOOM, which is able to map the Illumina/Solexa reads of 15x coverage of a human genome to the reference human genome in one CPU-day, allowing two mismatches, at full sensitivity. |
| 资助项目 | NSF China[60496320] ; NSF China[30500104] ; NSF China[30570393] ; NSF China[0324292] ; National Institutes of Health[HG001696] ; NSERC and Canada Research Chair program ; NSERC[RGPIN46506] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics |
| 语种 | 英语 |
| WOS记录号 | WOS:000260381200003 |
| 出版者 | OXFORD UNIV PRESS |
| 源URL | [http://119.78.100.204/handle/2XEOYT63/11173]  |
| 专题 | 中国科学院计算技术研究所期刊论文_英文 |
| 通讯作者 | Ma, Bin |
| 作者单位 | 1.Univ Western Ontario, Dept Comp Sci, London, ON N6A 5B8, Canada 2.Chinese Acad Sci, Comp Technol Inst, Beijing, Peoples R China 3.Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA 4.Univ Waterloo, David R Cheriton Sch Comp Sci, Waterloo, ON N2L 3G1, Canada |
| 推荐引用方式 GB/T 7714 | Lin, Hao,Zhang, Zefeng,Zhang, Michael Q.,et al. ZOOM! Zillions of oligos mapped[J]. BIOINFORMATICS,2008,24(21):2431-2437. |
| APA | Lin, Hao,Zhang, Zefeng,Zhang, Michael Q.,Ma, Bin,&Li, Ming.(2008).ZOOM! Zillions of oligos mapped.BIOINFORMATICS,24(21),2431-2437. |
| MLA | Lin, Hao,et al."ZOOM! Zillions of oligos mapped".BIOINFORMATICS 24.21(2008):2431-2437. |
入库方式： OAI收割
来源：计算技术研究所
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