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The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs

文献类型：期刊论文

作者He, Shunmin1,2,3,4,5,6; Yang, Zhen2,3,4; Skogerbo, Geir1,5; Ren, Fei2; Cui, Hongliang2; Zhao, Haitao3,4; Chen, Runsheng1,2,5; Zhao, Yi2
刊名CRITICAL REVIEWS IN MICROBIOLOGY
出版日期2008
卷号34期号:3-4页码:175-188
关键词miRNA siRNA Small noncoding RNA Viruses
ISSN号1040-841X
DOI10.1080/10408410802482008
英文摘要microRNAs (miRNAs) represent a class of noncoding RNA species, believed to be regulating gene expression by binding to complementary sites in the 3'UTRs of target mRNAs. They play important regulatory roles in various metabolic pathways in most eukaryotes. The recent discovery of virus encoded miRNAs suggests that viruses may be using them to regulate host and viral gene expression. Another class of closely related small interfering RNAs (siRNAs) also has been found within the HIV-1 genome and shown to be exerting a limited impact on virus reproduction. Additionally, an additional type of viral noncoding RNAs named small noncoding RNAs (sncRNAs) ranging from a few tens to a few hundred nucleotides in length, has also been identified. sncRNAs have a wide phylogenesis and high levels of expression, suggesting they may play an important roles in different species. Here we discuss the genomic organization, expression, conservation as well as potential function of virally encoded miRNA, siRNA, and sncRNAs.
资助项目National Sciences Foundation of China[30570393] ; National Sciences Foundation of China[30600729]
WOS研究方向Microbiology
语种英语
WOS记录号WOS:000260797900005
出版者INFORMA HEALTHCARE
源URL[http://119.78.100.204/handle/2XEOYT63/11354]  
专题中国科学院计算技术研究所期刊论文_英文
通讯作者Zhao, Yi
作者单位1.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Ctr Adv Comp Technol Res, Inst Comp Technol, Bioinformat Res Grp, Beijing, Peoples R China
3.Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Liver Surg, Beijing 100037, Peoples R China
4.Chinese Acad Sci, PUMC, Beijing, Peoples R China
5.Chinese Acad Sci, Bioinformat Lab, Beijing, Peoples R China
6.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 He, Shunmin,Yang, Zhen,Skogerbo, Geir,et al. The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs[J]. CRITICAL REVIEWS IN MICROBIOLOGY,2008,34(3-4):175-188.
APA He, Shunmin.,Yang, Zhen.,Skogerbo, Geir.,Ren, Fei.,Cui, Hongliang.,...&Zhao, Yi.(2008).The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs.CRITICAL REVIEWS IN MICROBIOLOGY,34(3-4),175-188.
MLA He, Shunmin,et al."The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs".CRITICAL REVIEWS IN MICROBIOLOGY 34.3-4(2008):175-188.

入库方式： OAI收割

来源：计算技术研究所

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