Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana
文献类型：期刊论文
| 作者 | Ji, Chang-Jiu1,2; Zeng, Guang-Zhi1; Han, Jing1,2; He, Wen-Jun1; Zhang, Yu-Mei1; Tan, Ning-Hua1 |
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2012-10-15 |
| 卷号 | 22期号:20页码:6377-6380 |
| 关键词 | Ziziphus mauritiana Nortriterpene Zizimauritic acids A-C Cytotoxicity Antibacterial activity |
| ISSN号 | 0960-894X |
| 通讯作者 | Tan, NH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China.,nhtan@mail.kib.ac.cn |
| 英文摘要 | Zizimauritic acids A-C (1-3), three novel nortriterpenes with a unique A-nor-E-seco spiro-lactone ceanothane-type triterpene skeleton, together with 3 known triterpenes ceanothenic acid (4), betulinic acid (5), and ceanothic acid (6), were isolated from the roots of Ziziphus mauritiana. Compounds 1-4 showed cytotoxicities with the IC50 values ranging from 5.05 to 11.94 mu g/ml, and compounds 1 and 3 showed an inhibitory effect on the growth of Staphylococcus aureus with the IC50 values 2.17 and 12.79 mu g/ml. A plausible biosynthetic pathway of compounds 1-3 was proposed. (c) 2012 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry, Medicinal; Chemistry, Organic |
| 类目[WOS] | Chemistry, Medicinal ; Chemistry, Organic |
| 研究领域[WOS] | Pharmacology & Pharmacy ; Chemistry |
| 关键词[WOS] | ZIZYPHUS-MAURITIANA ; CYCLOPEPTIDE ALKALOIDS ; LEAVES ; RHAMNACEAE ; TRITERPENE |
| 收录类别 | SCI ; IC |
| 资助信息 | National Natural Science Foundation of China [U1032602, 91013002, 30725048]; National New Drug Innovation Major Project of China [2011ZX09307-002-02]; National Basic Research Program of China [2009CB522300] |
| 语种 | 英语 |
| WOS记录号 | WOS:000309609500013 |
| 公开日期 | 2013-01-22 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/15938]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ji, Chang-Jiu,Zeng, Guang-Zhi,Han, Jing,et al. Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2012,22(20):6377-6380. |
| APA | Ji, Chang-Jiu,Zeng, Guang-Zhi,Han, Jing,He, Wen-Jun,Zhang, Yu-Mei,&Tan, Ning-Hua.(2012).Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,22(20),6377-6380. |
| MLA | Ji, Chang-Jiu,et al."Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 22.20(2012):6377-6380. |
入库方式： OAI收割
来源：昆明植物研究所
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