Intercedensides A-C, three new cytotoxic triterpene glycosides from the sea cucumber Mensamaria intercedens Lampert
文献类型：期刊论文
| 作者 | Zou ZR(邹峥嵘) ; Yi YH(易杨华) ; Wu HM(吴厚铭) ; Wu JH(吴久红) ; Chih-Chaung Liaw ; Kuo-Hsiumg Lee |
| 刊名 | J. Nat. Prod.
 |
| 出版日期 | 2003 |
| 卷号 | 66期号:8页码:1055-1060 |
| ISSN号 | 0163-3864 |
| 其他题名 | Intercedensides A-C, 二色卓片海参中的三个新三萜皂甙 |
| 通讯作者 | 易杨华 |
| 英文摘要 | Three new triterpene glycosides. Intercedensides A (1), B (2). And C (3), were isolated from the sea cucumber Mensamria infeTcedens Lampert. Which is found in the South China Sea. And their structures have been elucidated by spectroscopic analysis (NMR and ESIMS) and chemical transformations. Intercedensides A (1) and C (3) have a conjugated double bond (22E.24-diene) in the side chain of the aglycon. Intercedenside B (2) has two β-o-xylose and two sulfate groups in the carbohydrate chain. II tfir-ee glycosides showed significant cytotoxicity against 1O human tumor cell lines with Edso in the range 0.6-4.0 pg/mL. Intercedenside A (1) exhibited significant in vivo antineoplastic activity against mouse Lewis lung cancer and mouse SI80 sarcoma. On the basis of these initially promising results, intercedensides A-C merit further study as potential anticancer agents. |
| 学科主题 | 天然产物有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/np030064y |
| 语种 | 英语 |
| WOS记录号 | WOS:000184942300004 |
| 公开日期 | 2013-02-21 |
| 源URL | [http://202.127.28.38/handle/331003/17317]  |
| 专题 | 上海有机化学研究所_上海有机化学研究所 |
| 推荐引用方式 GB/T 7714 | Zou ZR,Yi YH,Wu HM,et al. Intercedensides A-C, three new cytotoxic triterpene glycosides from the sea cucumber Mensamaria intercedens Lampert[J]. J. Nat. Prod.,2003,66(8):1055-1060. |
| APA | 邹峥嵘,易杨华,吴厚铭,吴久红,Chih-Chaung Liaw,&Kuo-Hsiumg Lee.(2003).Intercedensides A-C, three new cytotoxic triterpene glycosides from the sea cucumber Mensamaria intercedens Lampert.J. Nat. Prod.,66(8),1055-1060. |
| MLA | 邹峥嵘,et al."Intercedensides A-C, three new cytotoxic triterpene glycosides from the sea cucumber Mensamaria intercedens Lampert".J. Nat. Prod. 66.8(2003):1055-1060. |
入库方式： OAI收割
来源：上海有机化学研究所
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