Time-Dependent Oxidative Stress Responses of Crucian Carp (Carassius auratus) to Intraperitoneal Injection of Extracted Microcystins
文献类型：期刊论文
| Author | Zhang, X.2; Xie, P.1,2; Li, D.2; Tang, R.2; Lei, H.1; Zhao, Y.2 |
| Source | BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
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| Issued Date | 2009-05-01 |
| Volume | 82Issue:5Pages:574-578 |
| Keyword | Crucian carp Extracted microcystins Oxidative stress Time-dependent |
| ISSN | 0007-4861 |
| Corresponding Author | Xie, P, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China |
| Abstract | This study was conducted to investigate time-dependent changes in oxidative enzymes in liver of crucian carp after intraperitoneally injection with extracted microcystins 600 and 150 mu g kg(-1) body weight. The results showed that activities of antioxidant enzymes, including superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase generally exhibited a rapid increase in early phase (1-3 h post injection), but gradually decreased afterwards (12-48 h) compared with the control, with an evident time-dependent effect. These zigzag changes over time contributed a better understanding on oxidative stress caused by microcystins in fish. |
| English Abstract | This study was conducted to investigate time-dependent changes in oxidative enzymes in liver of crucian carp after intraperitoneally injection with extracted microcystins 600 and 150 mu g kg(-1) body weight. The results showed that activities of antioxidant enzymes, including superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase generally exhibited a rapid increase in early phase (1-3 h post injection), but gradually decreased afterwards (12-48 h) compared with the control, with an evident time-dependent effect. These zigzag changes over time contributed a better understanding on oxidative stress caused by microcystins in fish. |
| WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
| Subject | Environmental Sciences; Toxicology |
| WOS Subject | Environmental Sciences ; Toxicology |
| WOS Subject Extended | Environmental Sciences & Ecology ; Toxicology |
| WOS Keyword Plus | PLASMA BIOCHEMICAL RESPONSES ; RAT-LIVER ; EXPOSURE ; LR ; TISSUES |
| Sponsorship | Huazhong Agricultural University and the National Natural Science Foundation of China [30530170] |
| Indexed Type | SCI |
| Language | 英语 |
| WOS ID | WOS:000264317600010 |
| Available Date | 2010-10-13 |