中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Time-Dependent Oxidative Stress Responses of Crucian Carp (Carassius auratus) to Intraperitoneal Injection of Extracted Microcystins

文献类型:期刊论文

AuthorZhang, X.2; Xie, P.1,2; Li, D.2; Tang, R.2; Lei, H.1; Zhao, Y.2
SourceBULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
Issued Date2009-05-01
Volume82Issue:5Pages:574-578
KeywordCrucian carp Extracted microcystins Oxidative stress Time-dependent
ISSN0007-4861
Corresponding AuthorXie, P, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China
AbstractThis study was conducted to investigate time-dependent changes in oxidative enzymes in liver of crucian carp after intraperitoneally injection with extracted microcystins 600 and 150 mu g kg(-1) body weight. The results showed that activities of antioxidant enzymes, including superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase generally exhibited a rapid increase in early phase (1-3 h post injection), but gradually decreased afterwards (12-48 h) compared with the control, with an evident time-dependent effect. These zigzag changes over time contributed a better understanding on oxidative stress caused by microcystins in fish.
English AbstractThis study was conducted to investigate time-dependent changes in oxidative enzymes in liver of crucian carp after intraperitoneally injection with extracted microcystins 600 and 150 mu g kg(-1) body weight. The results showed that activities of antioxidant enzymes, including superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase generally exhibited a rapid increase in early phase (1-3 h post injection), but gradually decreased afterwards (12-48 h) compared with the control, with an evident time-dependent effect. These zigzag changes over time contributed a better understanding on oxidative stress caused by microcystins in fish.
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
SubjectEnvironmental Sciences; Toxicology
WOS SubjectEnvironmental Sciences ; Toxicology
WOS Subject ExtendedEnvironmental Sciences & Ecology ; Toxicology
WOS Keyword PlusPLASMA BIOCHEMICAL RESPONSES ; RAT-LIVER ; EXPOSURE ; LR ; TISSUES
SponsorshipHuazhong Agricultural University and the National Natural Science Foundation of China [30530170]
Indexed TypeSCI
Language英语
WOS IDWOS:000264317600010
Available Date2010-10-13