Highly regioselective synthesis of trisubstituted allenes via lithiation of 1-aryl-3-alkylpropadiene, subsequent transmetalation, and Pd-catalyzed Negishi coupling reaction
文献类型：期刊论文
| 作者 | Zhao JB(赵金波) ; Liu Y(刘宇) ; Ma SM(麻生明) |
| 刊名 | Org. Lett.
 |
| 出版日期 | 2008 |
| 卷号 | 10期号:8页码:1521-1523 |
| ISSN号 | 1523-7060 |
| 其他题名 | Highly regioselective synthesis of trisubstituted allenes via lithiation of 1-aryl-3-alkylpropadiene, subsequent transmetalation, and Pd-catalyzed Negishi coupling reaction |
| 通讯作者 | 麻生明 |
| 英文摘要 | A novel methodology for the synthesis-of trisubstituted allenes is reported. Lithiation of 1-aryl-3-alkylpropadienes and subsequent transmetalation with zinc bromide followed by Pd-catalyzed Negishi coupling reactions with halides afforded the corresponding trisubstituted allenes in a highly regioselective fashion with moderate to excellent yields. A plausible regioselective lithiation mechanism was proposed on the basis of deuterium labeling experiments. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/ol8001909 |
| 语种 | 英语 |
| WOS记录号 | WOS:000254908000005 |
| 公开日期 | 2013-01-16 |
| 源URL | [http://202.127.28.38/handle/331003/12172]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhao JB,Liu Y,Ma SM. Highly regioselective synthesis of trisubstituted allenes via lithiation of 1-aryl-3-alkylpropadiene, subsequent transmetalation, and Pd-catalyzed Negishi coupling reaction[J]. Org. Lett.,2008,10(8):1521-1523. |
| APA | 赵金波,刘宇,&麻生明.(2008).Highly regioselective synthesis of trisubstituted allenes via lithiation of 1-aryl-3-alkylpropadiene, subsequent transmetalation, and Pd-catalyzed Negishi coupling reaction.Org. Lett.,10(8),1521-1523. |
| MLA | 赵金波,et al."Highly regioselective synthesis of trisubstituted allenes via lithiation of 1-aryl-3-alkylpropadiene, subsequent transmetalation, and Pd-catalyzed Negishi coupling reaction".Org. Lett. 10.8(2008):1521-1523. |
入库方式： OAI收割
来源：上海有机化学研究所
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