Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts
文献类型：期刊论文
| 作者 | Zhang, Xuezhen1; Xie, Ping1,2; Wang, Weimin1; Li, Dapeng1,2; Shi, Zechao3 |
| 刊名 | FISH PHYSIOLOGY AND BIOCHEMISTRY
 |
| 出版日期 | 2008-12-01 |
| 卷号 | 34期号:4页码:323-329 |
| 关键词 | Carassius auratus Cyanobacterial extracts Plasma Biochemistry |
| ISSN号 | 0920-1742 |
| 通讯作者 | Xie, P, Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China |
| 中文摘要 | Healthy crucian carp (Carassius auratus) were treated by intraperitoneal (i.p.) injection of crude cyanobacterial extracts at two doses, 50 and 200 mu g MC-LR equiv kg(-1) BW. High mortality (100%) was observed within 60 h post injection in the high-dose group. In the treated fish, activities of four plasma enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH), all showed substantial increases, with both dose and time-dependent effects. These increases of enzyme activity indicate severe impairment occurred in the liver of crucian carp over time. Plasma concentrations of energy-related biomolecules including glucose (GLU), cholesterol (CHO), triglyceride (TG), and total protein (TP) showed marked changes in the high-dose group, possibly a nutritional imbalance correlated with the liver injury caused by intraperitoneal exposure to crude cyanobacterial extracts. |
| 英文摘要 | Healthy crucian carp (Carassius auratus) were treated by intraperitoneal (i.p.) injection of crude cyanobacterial extracts at two doses, 50 and 200 mu g MC-LR equiv kg(-1) BW. High mortality (100%) was observed within 60 h post injection in the high-dose group. In the treated fish, activities of four plasma enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH), all showed substantial increases, with both dose and time-dependent effects. These increases of enzyme activity indicate severe impairment occurred in the liver of crucian carp over time. Plasma concentrations of energy-related biomolecules including glucose (GLU), cholesterol (CHO), triglyceride (TG), and total protein (TP) showed marked changes in the high-dose group, possibly a nutritional imbalance correlated with the liver injury caused by intraperitoneal exposure to crude cyanobacterial extracts. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Biochemistry & Molecular Biology; Fisheries; Physiology |
| 类目[WOS] | Biochemistry & Molecular Biology ; Fisheries ; Physiology |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Fisheries ; Physiology |
| 关键词[WOS] | CYCLIC PEPTIDE TOXIN ; MICROCYSTIN-LR ; CYPRINUS-CARPIO ; ONCORHYNCHUS-MYKISS ; RAINBOW-TROUT ; DANIO-RERIO ; SILVER CARP ; FISH ; TOXICITY ; ACCUMULATION |
| 收录类别 | SCI |
| 资助信息 | Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] |
| 语种 | 英语 |
| WOS记录号 | WOS:000260512800004 |
| 公开日期 | 2010-10-13 |
| 源URL | [http://ir.ihb.ac.cn/handle/152342/7966]  |
| 专题 | 水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文 |
| 作者单位 | 1.Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China 2.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430070, Peoples R China 3.Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Jinzhou 434000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xuezhen,Xie, Ping,Wang, Weimin,et al. Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts[J]. FISH PHYSIOLOGY AND BIOCHEMISTRY,2008,34(4):323-329. |
| APA | Zhang, Xuezhen,Xie, Ping,Wang, Weimin,Li, Dapeng,&Shi, Zechao.(2008).Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts.FISH PHYSIOLOGY AND BIOCHEMISTRY,34(4),323-329. |
| MLA | Zhang, Xuezhen,et al."Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts".FISH PHYSIOLOGY AND BIOCHEMISTRY 34.4(2008):323-329. |
入库方式： OAI收割
来源：水生生物研究所
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