中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Investigation of Biological Property of Nanohydroxyapatite Materials

文献类型:期刊论文

作者X. F. Pang ; H. W. Zhou ; J. L. Liu
刊名Journal of Nanoscience and Nanotechnology
出版日期2012
卷号12期号:2页码:894-901
关键词Nanohydroxyapatite Cell Proliferation Biological Function Toxicity Infrared Spectrum Electrophoresis Human Serum Albumin Molecular Structure nano-hydroxyapatite in-vitro nanoparticles proteins nanostructures cytotoxicity ir
ISSN号1533-4880
中文摘要The biological effects of nanohydroxyapatites and its cell toxicity have been studied using the MU and ALP method, infrared spectrum of absorption and electrophoresis method, respectively. The nanohydroxyapatites are prepared and made by using sol-gel method, in which the parameters of process and reaction are controlled as: pH > 9, Ca/P = 1.67, sintering temperature of 1100 degrees C and sintering time 2 hours. Studied results show that nanohydroxyapatites can interact with human serum albumin and change its second structure and weight of molecules. We find that the nanohydroxyapatites and complex of nanoHAP + nanoCrO(2) can all restrain the proliferation of MG63 cells, but their toxicities are first degree or minor, the toxicity of the complex is smaller than that of pure nanohydroxyapatites.
原文出处://WOS:000303280000005
公开日期2013-02-05
源URL[http://ir.imr.ac.cn/handle/321006/60187]  
专题金属研究所_中国科学院金属研究所
推荐引用方式
GB/T 7714
X. F. Pang,H. W. Zhou,J. L. Liu. Investigation of Biological Property of Nanohydroxyapatite Materials[J]. Journal of Nanoscience and Nanotechnology,2012,12(2):894-901.
APA X. F. Pang,H. W. Zhou,&J. L. Liu.(2012).Investigation of Biological Property of Nanohydroxyapatite Materials.Journal of Nanoscience and Nanotechnology,12(2),894-901.
MLA X. F. Pang,et al."Investigation of Biological Property of Nanohydroxyapatite Materials".Journal of Nanoscience and Nanotechnology 12.2(2012):894-901.

入库方式: OAI收割

来源:金属研究所

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