Investigation of Biological Property of Nanohydroxyapatite Materials
文献类型:期刊论文
作者 | X. F. Pang ; H. W. Zhou ; J. L. Liu |
刊名 | Journal of Nanoscience and Nanotechnology
![]() |
出版日期 | 2012 |
卷号 | 12期号:2页码:894-901 |
关键词 | Nanohydroxyapatite Cell Proliferation Biological Function Toxicity Infrared Spectrum Electrophoresis Human Serum Albumin Molecular Structure nano-hydroxyapatite in-vitro nanoparticles proteins nanostructures cytotoxicity ir |
ISSN号 | 1533-4880 |
中文摘要 | The biological effects of nanohydroxyapatites and its cell toxicity have been studied using the MU and ALP method, infrared spectrum of absorption and electrophoresis method, respectively. The nanohydroxyapatites are prepared and made by using sol-gel method, in which the parameters of process and reaction are controlled as: pH > 9, Ca/P = 1.67, sintering temperature of 1100 degrees C and sintering time 2 hours. Studied results show that nanohydroxyapatites can interact with human serum albumin and change its second structure and weight of molecules. We find that the nanohydroxyapatites and complex of nanoHAP + nanoCrO(2) can all restrain the proliferation of MG63 cells, but their toxicities are first degree or minor, the toxicity of the complex is smaller than that of pure nanohydroxyapatites. |
原文出处 | |
公开日期 | 2013-02-05 |
源URL | [http://ir.imr.ac.cn/handle/321006/60187] ![]() |
专题 | 金属研究所_中国科学院金属研究所 |
推荐引用方式 GB/T 7714 | X. F. Pang,H. W. Zhou,J. L. Liu. Investigation of Biological Property of Nanohydroxyapatite Materials[J]. Journal of Nanoscience and Nanotechnology,2012,12(2):894-901. |
APA | X. F. Pang,H. W. Zhou,&J. L. Liu.(2012).Investigation of Biological Property of Nanohydroxyapatite Materials.Journal of Nanoscience and Nanotechnology,12(2),894-901. |
MLA | X. F. Pang,et al."Investigation of Biological Property of Nanohydroxyapatite Materials".Journal of Nanoscience and Nanotechnology 12.2(2012):894-901. |
入库方式: OAI收割
来源:金属研究所
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。