Preliminary study of anti-infective function of a copper-bearing stainless steel
文献类型：期刊论文
| 作者 | L. Ren ; K. Yang ; L. Guo ; H. W. Chai |
| 刊名 | Materials Science & Engineering C-Materials for Biological Applications
 |
| 出版日期 | 2012 |
| 卷号 | 32期号:5页码:1204-1209 |
| 关键词 | Bacterial infection Cu-bearing Antibacterial stainless steel Anti-infection antibacterial properties staphylococcus-aureus corrosion-resistance infections biofilms osteomyelitis bacteria metals model ions |
| ISSN号 | 0928-4931 |
| 中文摘要 | In this study the copper (Cu)-bearing stainless steel was developed to reduce the incidence of implant-associated infections in clinical areas. A 317L austenitic stainless steel containing 4.5% Cu (317L-Cu SS) was designed and fabricated, and its anti-infective function was preliminarily studied both in vitro and in vivo by means of antibacterial test, confocal laser scanning microscope (CLSM) and scanning electron microscopy (SEM) observations, and animal implantation. The results indicated that the 317L-Cu SS possessed strong antibacterial rates against both Escherichia coil and Staphylococcus aureus, and showed anti-infective ability by inhibiting the formation of bacterial bio-film on surface of the steel due to the release of Cu ions from the steel surface. The microbiological and histological evaluations from animal implantation further proved that the 317L-Cu SS could obviously reduce the happening of bacterial infection, and is potential to be used as a new class of surgical implant material with anti-infective function. (C) 2012 Elsevier B.V. All rights reserved. |
| 原文出处 | |
| 公开日期 | 2013-02-05 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/60201]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | L. Ren,K. Yang,L. Guo,et al. Preliminary study of anti-infective function of a copper-bearing stainless steel[J]. Materials Science & Engineering C-Materials for Biological Applications,2012,32(5):1204-1209. |
| APA | L. Ren,K. Yang,L. Guo,&H. W. Chai.(2012).Preliminary study of anti-infective function of a copper-bearing stainless steel.Materials Science & Engineering C-Materials for Biological Applications,32(5),1204-1209. |
| MLA | L. Ren,et al."Preliminary study of anti-infective function of a copper-bearing stainless steel".Materials Science & Engineering C-Materials for Biological Applications 32.5(2012):1204-1209. |
入库方式： OAI收割
来源：金属研究所
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