Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans
文献类型：期刊论文
| 作者 | Chai Z(柴卓) ; Jie ZF(解正峰) ; Liu XY(刘心源) ; Zhao G(赵刚) ; Wang JD(王吉德) |
| 刊名 | J. Org. Chem.
 |
| 出版日期 | 2008 |
| 卷号 | 73期号:7页码:2947-2950 |
| ISSN号 | 0022-3263 |
| 其他题名 | 有机锌试剂对2-炔醛的串联加成-环化反应：高效区域选择性合成1，3-二氢苯并呋喃和四取代呋喃 |
| 通讯作者 | 赵刚 ; 王吉德 |
| 英文摘要 | The enantioselective addition of organozinc reagents to some 2-alkynyl benzaldehydes and the subsequent regioselective cyclization step was performed in one pot to form chiral 1,3-dihydroisobenzofurans with good product yields and excellent regio- and enantioselectivities. In the case of 2-alkynyl-cycloalkene aldehydes, tetrasubstituted furans were obtained in good product yields through a 1, 5-hydride shift of the preformed cyclization product. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/jo800029m |
| 语种 | 英语 |
| WOS记录号 | WOS:000254544800067 |
| 公开日期 | 2013-02-26 |
| 源URL | [http://202.127.28.38/handle/331003/20745]  |
| 专题 | 上海有机化学研究所_中科院天然产物有机化学重点实验室 |
| 推荐引用方式 GB/T 7714 | Chai Z,Jie ZF,Liu XY,et al. Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans[J]. J. Org. Chem.,2008,73(7):2947-2950. |
| APA | 柴卓,解正峰,刘心源,赵刚,&王吉德.(2008).Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans.J. Org. Chem.,73(7),2947-2950. |
| MLA | 柴卓,et al."Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans".J. Org. Chem. 73.7(2008):2947-2950. |
入库方式： OAI收割
来源：上海有机化学研究所
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