Chiral recognition of zinc(II) ion complexes composed of bicyclo[3.3.0] octane-2,6-diol and s-Naproxen probed by collisional-induced dissociation
文献类型：期刊论文
| 作者 | Yu CT(余翀天) ; Guo YL(郭寅龙) ; Chen GQ(陈国强) ; Zhong YW(钟羽武) |
| 刊名 | J. Am. Soc. Mass Spectrom.
 |
| 出版日期 | 2004 |
| 卷号 | 15期号:6页码:795-802 |
| ISSN号 | 1044-0305 |
| 其他题名 | 碰撞诱导解离研究s-萘普生和双环[3.3.0]-2,6-辛二醇构成的锌簇合离子的手性识别机制 |
| 通讯作者 | 郭寅龙 |
| 英文摘要 | Chiral recognition of racemic bicyclo[3.3.0] octane-2,6-diol(B) was achieved in the gas phase using s-Naproxen(A) as reference, using the kinetics of competitive unimolecule dissociation of tetrameric zinc(II)-bound complexes by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometer(ESI-FTMS). As undergoing a mild competitive collision-induced dissociation(CID) experiment with a constant pressure argon gas introduced by leak valve, the tetrameric cluster ion [A(2)B(2)Z(n)(II)-H](+) forms only two trimeric ions and R,,,,, is subsequently obtained in the kinetic method. Further studies obtained the difference of Gibbs free energy of [ABZ(n)(II)-H](+)(DeltaDeltaG(ABZn)(II)-H](+) by dissociating [A(2)BZ(n)(II)-H](+), resulting two fragment ions [ABZ(n)(II)-H](+) and [A(2)Z(n)(II)-H](+), which can be established to a linear relationship between DeltaDeltaG([ABZn(II)-H])(+) and R'(chiral) basing on the kinetic method. The value of R'(chiral) suggested that DeltaDeltaG([ABZn(II))-(+)(H]) could be regarded as zero. Meanwhile, dissociation of [AB(2)Z(n)(II)-H](+) generated only one daughter ion [ABZ(n)(II)-H](+) in a stable pressure. Thus, a linear relationship was established between the difference of Gibbs free energy of [AB(2)Z(n)(II)H](+)(DeltaDeltaG([AB2Zn(II)-H])(+)) and R'(chiral) if the DeltaDeltaG([ABZn(II)-H]+) can be negligible. Because there is also a linear relationship of R'(chiral) in the tetrameric ion [A(2)B(2)Zn(II)-H](+) and the Gibbs energy difference of trimeric cluster ion [A(2)BZ(n)(+) (II)-H](DeltaDeltaG([A2BZn(II)-H])(+)) plus that of [AB(2)Zn(II)-H](+), DeltaDeltaG([A2BZn(II)-H]+]) is easy to be calculated in the dissociation process of tetrameric ion. Stable of R'(chiral), R'(chiral), and R''(chiral) under different pressures show T-eff does not affect the chiral recognition of cluster ions in the condition selected. If an only-one-daughter-ion fragment process of [A(2)BZ(n)(II)-H](+) was existed, R'''(chiral) relating to this dissociation would be calculated just like R"(chiral), of [AB(2)Z(n)(II)-H](+) does. Conclusion was obtained that [A(2)BZ(n)(II)-H](+) makes more contribution to chiral recognition of tetrameric ion measured by kinetic method than [AB(2)Z(n)(II)-H](+) does as R'(chiral) and R"(chiral) were applied as index to evaluate the Gibbs free energy difference of these two trimeric cluster ions. Further discussion shows that steric interactions and pi-pi stacking interactions are the major factors responsible for the observed efficient chiral recognition in this system. (C) 2004 American Society for Mass Spectrometry. |
| 学科主题 | 分析化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1016/j.jasms.2004.02.003 |
| 语种 | 英语 |
| WOS记录号 | WOS:000221707900004 |
| 公开日期 | 2013-02-25 |
| 源URL | [http://202.127.28.38/handle/331003/19860]  |
| 专题 | 上海有机化学研究所_分析化学研究室 |
| 推荐引用方式 GB/T 7714 | Yu CT,Guo YL,Chen GQ,et al. Chiral recognition of zinc(II) ion complexes composed of bicyclo[3.3.0] octane-2,6-diol and s-Naproxen probed by collisional-induced dissociation[J]. J. Am. Soc. Mass Spectrom.,2004,15(6):795-802. |
| APA | 余翀天,郭寅龙,陈国强,&钟羽武.(2004).Chiral recognition of zinc(II) ion complexes composed of bicyclo[3.3.0] octane-2,6-diol and s-Naproxen probed by collisional-induced dissociation.J. Am. Soc. Mass Spectrom.,15(6),795-802. |
| MLA | 余翀天,et al."Chiral recognition of zinc(II) ion complexes composed of bicyclo[3.3.0] octane-2,6-diol and s-Naproxen probed by collisional-induced dissociation".J. Am. Soc. Mass Spectrom. 15.6(2004):795-802. |
入库方式： OAI收割
来源：上海有机化学研究所
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