Studies of keratins in tongue coating samples of hepatitis B patients by mass spectrometry
文献类型：期刊论文
| 作者 | Fang F(方芳) ; Liu P(刘平) ; Wang HY(王昊阳) ; Zhang L(张立) ; Zhang J(张菁) ; Gao YP(高玉平) ; Ceng LM(曾丽敏) ; Guo YL(郭寅龙) |
| 刊名 | Rapid Commun. Mass Spectrom.
 |
| 出版日期 | 2009 |
| 卷号 | 23期号:11页码:1703-1709 |
| ISSN号 | 0951-4198 |
| 其他题名 | B型肝炎患者舌苔中角蛋白的质谱法研究 |
| 通讯作者 | 刘平 ; 郭寅龙 |
| 英文摘要 | Pooled tongue coating samples from 64 hepatitis B patients and 24 healthy adults were studied and a major band of differential proteins was found by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). The differential proteins in this band were identified and proved to be keratins by liquid chromatography/tandem mass spectrometry (LC/MS/MS) and Western blot analysis. Furthermore, relative quantification of the identified keratins was performed via using stable isotopic labeling and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), showing the higher expression level of these keratins in tongue coating samples of hepatitis B patients than healthy adults. These results provided additional information to understand the medical diagnosis depending on the tongue coating. Copyright (C) 2009 John Wiley & Sons, Ltd. |
| 学科主题 | 分析化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1002/rcm.4060 |
| 语种 | 英语 |
| WOS记录号 | WOS:000266724000020 |
| 公开日期 | 2013-02-25 |
| 源URL | [http://202.127.28.38/handle/331003/19982]  |
| 专题 | 上海有机化学研究所_分析化学研究室 |
| 推荐引用方式 GB/T 7714 | Fang F,Liu P,Wang HY,et al. Studies of keratins in tongue coating samples of hepatitis B patients by mass spectrometry[J]. Rapid Commun. Mass Spectrom.,2009,23(11):1703-1709. |
| APA | 方芳.,刘平.,王昊阳.,张立.,张菁.,...&郭寅龙.(2009).Studies of keratins in tongue coating samples of hepatitis B patients by mass spectrometry.Rapid Commun. Mass Spectrom.,23(11),1703-1709. |
| MLA | 方芳,et al."Studies of keratins in tongue coating samples of hepatitis B patients by mass spectrometry".Rapid Commun. Mass Spectrom. 23.11(2009):1703-1709. |
入库方式： OAI收割
来源：上海有机化学研究所
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