Synthesis of bidesmosidic dihydrodiosgenin saponins bearing a 3-O-beta-chacotriosyl moiety
文献类型：期刊论文
| 作者 | Yichun Zhang ; Li YX(李英霞) ; Zhu SL(朱石磊) ; Huashi Guan ; Lin F(林峰) ; Yu B(俞飚) |
| 刊名 | Carbohydr. Res.
 |
| 出版日期 | 2004 |
| 卷号 | 339期号:10页码:1753-1759 |
| ISSN号 | 0008-6215 |
| 其他题名 | 锁链二氢鼠蓣皂甙的合成 |
| 通讯作者 | 李英霞 ; 俞飚 |
| 英文摘要 | 3-O-beta-Chacotriosyl-26-O-beta-D-glucopyranosyl-(25R)-furost-5-en (1), a mimic of the antitumor active proto-dioscin, was concisely synthesized from diosgenin in a linear nine steps and in 17% overall yield. Its congeners with a alpha-L-rhamnopyranosyl, beta-lactosyl, or without a substituent at the 26-OH (13-15) were also prepared. Compound 1, as well as 13-15, did not show any inhibition against tumor cells, implying that proto-dioscin might be also inactive, but readily converted into the antitumor active dioscin. (C) 2004 Elsevier Ltd. All rights reserved. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1016/j.carres.2004.04.014 |
| 语种 | 英语 |
| WOS记录号 | WOS:000222746900010 |
| 公开日期 | 2013-02-25 |
| 源URL | [http://202.127.28.38/handle/331003/18983]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Yichun Zhang,Li YX,Zhu SL,et al. Synthesis of bidesmosidic dihydrodiosgenin saponins bearing a 3-O-beta-chacotriosyl moiety[J]. Carbohydr. Res.,2004,339(10):1753-1759. |
| APA | Yichun Zhang,李英霞,朱石磊,Huashi Guan,林峰,&俞飚.(2004).Synthesis of bidesmosidic dihydrodiosgenin saponins bearing a 3-O-beta-chacotriosyl moiety.Carbohydr. Res.,339(10),1753-1759. |
| MLA | Yichun Zhang,et al."Synthesis of bidesmosidic dihydrodiosgenin saponins bearing a 3-O-beta-chacotriosyl moiety".Carbohydr. Res. 339.10(2004):1753-1759. |
入库方式： OAI收割
来源：上海有机化学研究所
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