A Hydrogen Peroxide Based Access to Qinghaosu (Artemisinin)
文献类型：期刊论文
| 作者 | Hao HD(郝宏东) ; Li Y(李云) ; Han WB(韩伟博) ; Wu YK(伍贻康) |
| 刊名 | Org. Lett.
 |
| 出版日期 | 2011 |
| 卷号 | 13期号:16页码:4212-4215 |
| ISSN号 | 1523-7060 |
| 其他题名 | 一种基于双氧水合成青蒿素的方法 |
| 通讯作者 | 伍贻康 |
| 英文摘要 | Attachment of H(2)O(2) onto the highly hindered quaternary C-12a in an advanced qinghaosu (artemisinin) precursor has been achieved through a facile perhydrolysis of a spiro epoxy ring with the aid of a previously unknown molybdenum species without Involving any special equipment or complicated operations. The resultant beta-hydroxyhydroperoxide can be further elaborated Into qinghaosu, illustrating an entry fundamentally different from the existing ones to this outstanding natural product of great importance in malaria chemotherapy. |
| 学科主题 | 天然产物有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/ol2015434 |
| 语种 | 英语 |
| WOS记录号 | WOS:000293759100016 |
| 公开日期 | 2013-02-25 |
| 源URL | [http://202.127.28.38/handle/331003/20465]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Hao HD,Li Y,Han WB,et al. A Hydrogen Peroxide Based Access to Qinghaosu (Artemisinin)[J]. Org. Lett.,2011,13(16):4212-4215. |
| APA | 郝宏东,李云,韩伟博,&伍贻康.(2011).A Hydrogen Peroxide Based Access to Qinghaosu (Artemisinin).Org. Lett.,13(16),4212-4215. |
| MLA | 郝宏东,et al."A Hydrogen Peroxide Based Access to Qinghaosu (Artemisinin)".Org. Lett. 13.16(2011):4212-4215. |
入库方式： OAI收割
来源：上海有机化学研究所
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