Site-Specific Fluorescent Labeling Approaches for Naringenin, an Essential Flavonone in Plant Nitrogen-Fixation Signaling Pathways
文献类型：期刊论文
| 作者 | Chen L(陈磊) ; Li FQ(李风庆) ; Hou BH(侯碧和) ; Hong GF(洪国藩) ; Yao ZJ(姚祝军) |
| 刊名 | J. Org. Chem.
 |
| 出版日期 | 2008 |
| 卷号 | 73期号:21页码:8279-8285 |
| ISSN号 | 0022-3263 |
| 其他题名 | 植物固氮信号分子柚皮素位置专一性的荧光标记 |
| 通讯作者 | 洪国藩 ; 姚祝军 |
| 英文摘要 | In search of an appropriate position for the fluorescent labeling. six chemically available positions of the flavonone core of naringenin have been examined. A number of azido-containing naringenin derivatives were accordingly prepared in various site-specific fashions. and the Mild CU(I)-catalyzed Huisgen 1-3-dipolar cycloaddition successfully served as the common "Click" labeling tool in the final steps. Oil the basis of the biological activities of the first batch of labeled compounds, further optimization at the C-6 position of naringenin finally afforded naringenin-flu (27). which acquired 20% of the potency of naringenin and presented good optical properties. Entry of naringenin-flu into living Rhizobium Cells was demonstrated by in vitro fluorescent imaging experiments. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/jo8014165 |
| 语种 | 英语 |
| WOS记录号 | WOS:000260533300018 |
| 公开日期 | 2013-02-26 |
| 源URL | [http://202.127.28.38/handle/331003/21105]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Chen L,Li FQ,Hou BH,et al. Site-Specific Fluorescent Labeling Approaches for Naringenin, an Essential Flavonone in Plant Nitrogen-Fixation Signaling Pathways[J]. J. Org. Chem.,2008,73(21):8279-8285. |
| APA | 陈磊,李风庆,侯碧和,洪国藩,&姚祝军.(2008).Site-Specific Fluorescent Labeling Approaches for Naringenin, an Essential Flavonone in Plant Nitrogen-Fixation Signaling Pathways.J. Org. Chem.,73(21),8279-8285. |
| MLA | 陈磊,et al."Site-Specific Fluorescent Labeling Approaches for Naringenin, an Essential Flavonone in Plant Nitrogen-Fixation Signaling Pathways".J. Org. Chem. 73.21(2008):8279-8285. |
入库方式： OAI收割
来源：上海有机化学研究所
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