Microcystin-RR-induced apoptosis in tobacco BY-2 cells
文献类型：期刊论文
| 作者 | Yin, Liyan; Huang, Jiaquan; Li, Wei; Liu, Yongding |
| 刊名 | TOXICON
 |
| 出版日期 | 2006-08-01 |
| 卷号 | 48期号:2页码:204-210 |
| ISSN号 | 0041-0101 |
| 关键词 | microcystin-RR tobacco BY-2 cells apoptosis flow cytometry transmission electron microscopy |
| 通讯作者 | Liu, YD, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China |
| 中文摘要 | Our previous studies showed that microcystin-RR could induce oxidative damage in plant cells as they do with animal cells. However, whether microcystin can induce plant cell apoptosis is still unknown. In this study, the morphological changes of tobacco BY-2 suspension cells exposed to microcystin-RR were observed under light microscopy and transmission electron microscopy, and apoptosis was clearly distinguished by intense perinuclear chromatin margination, condensation of nuclear chromatin after 6d exposure of 50 mg/L (about 50 mu M) microcystin-RR. We also found that microcystin-RR can induce tobacco cell apoptosis in a dose- and time-dependent manner with flow cytometry analysis. Our study provides the first evidence that microcystins can induce plant cell apoptosis. (c) 2006 Elsevier Ltd. All rights reserved. |
| 英文摘要 | Our previous studies showed that microcystin-RR could induce oxidative damage in plant cells as they do with animal cells. However, whether microcystin can induce plant cell apoptosis is still unknown. In this study, the morphological changes of tobacco BY-2 suspension cells exposed to microcystin-RR were observed under light microscopy and transmission electron microscopy, and apoptosis was clearly distinguished by intense perinuclear chromatin margination, condensation of nuclear chromatin after 6d exposure of 50 mg/L (about 50 mu M) microcystin-RR. We also found that microcystin-RR can induce tobacco cell apoptosis in a dose- and time-dependent manner with flow cytometry analysis. Our study provides the first evidence that microcystins can induce plant cell apoptosis. (c) 2006 Elsevier Ltd. All rights reserved. |
| 学科主题 | Pharmacology & Pharmacy; Toxicology |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Pharmacology & Pharmacy ; Toxicology |
| 研究领域[WOS] | Pharmacology & Pharmacy ; Toxicology |
| 关键词[WOS] | CYANOBACTERIAL TOXIN ; PROTEIN PHOSPHATASES ; LR ; INHIBITION ; HEPATOCYTES ; TOXICITY ; GROWTH ; PLANTS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000240050500008 |
| 公开日期 | 2010-10-13 |
| 源URL | [http://ir.ihb.ac.cn/handle/152342/8856]  |
| 专题 | 水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Bot Gardens, Wuhan 430072, Peoples R China 3.Chinese Acad Agr Sci, Oil Crops Res Inst, Wuhan 430062, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yin, Liyan,Huang, Jiaquan,Li, Wei,et al. Microcystin-RR-induced apoptosis in tobacco BY-2 cells[J]. TOXICON,2006,48(2):204-210. |
| APA | Yin, Liyan,Huang, Jiaquan,Li, Wei,&Liu, Yongding.(2006).Microcystin-RR-induced apoptosis in tobacco BY-2 cells.TOXICON,48(2),204-210. |
| MLA | Yin, Liyan,et al."Microcystin-RR-induced apoptosis in tobacco BY-2 cells".TOXICON 48.2(2006):204-210. |
入库方式： OAI收割
来源：水生生物研究所
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