Presence of estrogenic activity from emission of fossil fuel combustion as detected by a recombinant yeast bioassay
文献类型：期刊论文
| 作者 | Wang, JX; Wu, WZ; Henkelmann, B; You, L; Kettrup, A; Schramm, KW |
| 刊名 | ATMOSPHERIC ENVIRONMENT
 |
| 出版日期 | 2003-07-01 |
| 卷号 | 37期号:23页码:3225-3235 |
| 关键词 | fossil fuel emission estrogenic activity yeast bioassay |
| ISSN号 | 1352-2310 |
| 通讯作者 | Schramm, KW, GSF, Natl Res Ctr Environm & Hlth, Inst Ecol Chem, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany |
| 中文摘要 | Estrogenic activities of emission samples generated by fossil fuel combustion were investigated with human estrogen receptor (ER) recombinant yeast bioassay. The results showed that there were weak but clear estrogenic activities in combustion emissions of fossil fuels including coal, petroleum, and diesel. The estrogenic relative potency (RP) of fossil fuel combustion was the highest in petroleum-fired car, followed by coal-fired stove, diesel-fired agrimotor, coal-fired electric power station. On the other hand, the estrogenic relative inductive efficiency (RIE) was the highest in coal-fired stove and coal-fired electric power station, followed by petroleum-fired car and diesel-fired agrimotor. The estrogenic activities in the sub-fractions from chromatographic separation of emitted materials were also determined. The results indicated that different chemical fractions in these complex systems have different estrogenic potencies. The GC/MS analysis of the emission showed that there were many aromatic carbonyls, big molecular alcohol, PAHs and derivatives, and substituted phenolic compounds and derivatives which have been reported as environmental estrogens. The existence of estrogenic substances in fossil fuel combustion demands further investigation of their potential adverse effects on human and on the ecosystem. The magnitude of pollution due to global usage of fossil fuels makes it imperative to understand the issue of fossil fuel-derived endocrine activities and the associated health risks, particularly the aggregated risks stemmed from exposure to toxicants of multiple sources. (C) 2003 Elsevier Science Ltd. All rights reserved. |
| 英文摘要 | Estrogenic activities of emission samples generated by fossil fuel combustion were investigated with human estrogen receptor (ER) recombinant yeast bioassay. The results showed that there were weak but clear estrogenic activities in combustion emissions of fossil fuels including coal, petroleum, and diesel. The estrogenic relative potency (RP) of fossil fuel combustion was the highest in petroleum-fired car, followed by coal-fired stove, diesel-fired agrimotor, coal-fired electric power station. On the other hand, the estrogenic relative inductive efficiency (RIE) was the highest in coal-fired stove and coal-fired electric power station, followed by petroleum-fired car and diesel-fired agrimotor. The estrogenic activities in the sub-fractions from chromatographic separation of emitted materials were also determined. The results indicated that different chemical fractions in these complex systems have different estrogenic potencies. The GC/MS analysis of the emission showed that there were many aromatic carbonyls, big molecular alcohol, PAHs and derivatives, and substituted phenolic compounds and derivatives which have been reported as environmental estrogens. The existence of estrogenic substances in fossil fuel combustion demands further investigation of their potential adverse effects on human and on the ecosystem. The magnitude of pollution due to global usage of fossil fuels makes it imperative to understand the issue of fossil fuel-derived endocrine activities and the associated health risks, particularly the aggregated risks stemmed from exposure to toxicants of multiple sources. (C) 2003 Elsevier Science Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
| 学科主题 | Environmental Sciences; Meteorology & Atmospheric Sciences |
| 类目[WOS] | Environmental Sciences ; Meteorology & Atmospheric Sciences |
| 研究领域[WOS] | Environmental Sciences & Ecology ; Meteorology & Atmospheric Sciences |
| 关键词[WOS] | POLYCYCLIC AROMATIC-HYDROCARBONS ; DISRUPTING CHEMICALS ; LIGHT-DUTY ; ASSAY ; RECEPTOR ; BINDING ; HEALTH ; SCREEN ; BENZANTHRACENE ; GASOLINE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000184188500006 |
| 公开日期 | 2010-10-13 |
| 源URL | [http://ir.ihb.ac.cn/handle/152342/9682]  |
| 专题 | 水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文 |
| 作者单位 | 1.GSF, Natl Res Ctr Environm & Hlth, Inst Ecol Chem, D-85764 Neuherberg, Germany 2.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 3.Chem Ind Inst Toxicol, Res Triangle Pk, NC 27709 USA 4.Tech Univ Munich, Lehrstuhl Okol Chem & Umweltanalyt, D-85350 Freising Weihenstephan, Germany |
| 推荐引用方式 GB/T 7714 | Wang, JX,Wu, WZ,Henkelmann, B,et al. Presence of estrogenic activity from emission of fossil fuel combustion as detected by a recombinant yeast bioassay[J]. ATMOSPHERIC ENVIRONMENT,2003,37(23):3225-3235. |
| APA | Wang, JX,Wu, WZ,Henkelmann, B,You, L,Kettrup, A,&Schramm, KW.(2003).Presence of estrogenic activity from emission of fossil fuel combustion as detected by a recombinant yeast bioassay.ATMOSPHERIC ENVIRONMENT,37(23),3225-3235. |
| MLA | Wang, JX,et al."Presence of estrogenic activity from emission of fossil fuel combustion as detected by a recombinant yeast bioassay".ATMOSPHERIC ENVIRONMENT 37.23(2003):3225-3235. |
入库方式： OAI收割
来源：水生生物研究所
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