Synthesis of pennogenin utilizing the intact skeleton of diosgenin
文献类型：期刊论文
| 作者 | Tian WS(田伟生) ; Xu QH(许启海) ; Chen L(陈玲) ; Zhao CF(赵春丰) |
| 刊名 | Sci. China Ser. B-Chem.
 |
| 出版日期 | 2004 |
| 卷号 | 47期号:2页码:142-144 |
| ISSN号 | 1006-9291 |
| 其他题名 | 利用薯蓣皂甙元首次合成喷脑皂甙元 |
| 英文摘要 | The first synthesis of pennogenin, an aglycone of bioactive components of Chinese traditional medicine named "Chonglou"(Paris), starting from diosgenin, has been reported, which displays a new strategy of utilizing the resource compounds. According to this new strategy, the full and rational utilization of the intact skeleton and functional groups of starting material has been realized in the conversion of diosgenin to pennogenin. The key step for synthesis of pennogenin is the regioselective transformation of cholest-5-en-16,22-dion-3,26-diol to cholest-5,16-dien-22-on-3,26-diol, which can be used to synthesize other bioactive steroids such as cephalostatin and OSW-1. |
| 学科主题 | 天然产物有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1360/03yb0002 |
| 语种 | 英语 |
| WOS记录号 | WOS:000221119100008 |
| 公开日期 | 2013-03-11 |
| 源URL | [http://202.127.28.38/handle/331003/23838]  |
| 专题 | 上海有机化学研究所_中科院天然产物有机化学重点实验室 |
| 推荐引用方式 GB/T 7714 | Tian WS,Xu QH,Chen L,et al. Synthesis of pennogenin utilizing the intact skeleton of diosgenin[J]. Sci. China Ser. B-Chem.,2004,47(2):142-144. |
| APA | 田伟生,许启海,陈玲,&赵春丰.(2004).Synthesis of pennogenin utilizing the intact skeleton of diosgenin.Sci. China Ser. B-Chem.,47(2),142-144. |
| MLA | 田伟生,et al."Synthesis of pennogenin utilizing the intact skeleton of diosgenin".Sci. China Ser. B-Chem. 47.2(2004):142-144. |
入库方式： OAI收割
来源：上海有机化学研究所
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